Objective: To prospectively assess the efficacy of emesis induction for the recovery of gastric foreign objects in cats and to determine if any factors influenced recovery.
Animals: 22 client-owned cats.
Procedures: Cats for which emesis induction was deemed appropriate were administered an emetic agent by the attending clinician between October 2018 and April 2021. Data collected included whether emesis was successful in recovery in some or all of the foreign object, time from administration to emesis, number of emetic events, and type, length, width, and surface area of the material ingested.
Results: Of the 22 cats that had emesis attempted, 11 (50%) vomited some or all of the foreign object. The time from ingestion to presentation, time from the last meal, presence of food in the vomitus, type of the object, and length, width, and surface area of the object did not influence the likelihood of successful recovery with emesis induction. The most common object cats ingested were rubber bands.
Clinical Relevance: Recovery of gastric foreign objects in cats with emesis induction alone may be successful 50% of the time. The type and size of the object is unlikely to influence whether or not emesis will be successful. This information can help prepare cat-owners for expectations and outcomes following attempts at emesis induction.
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http://dx.doi.org/10.2460/javma.23.03.0176 | DOI Listing |
Clin Transl Gastroenterol
January 2025
Immunic AG, Lochhamer Schlag 21, 82166 Gräfelfing, Germany.
Introduction: Vidofludimus calcium (VidoCa) is a dihydroorotate dehydrogenase (DHODH) inhibitor that demonstrated efficacy in immune-related diseases. This study assessed the safety and efficacy of VidoCa in patients with active ulcerative colitis (UC).
Methods: This placebo-controlled, phase 2 trial randomized adults with moderate-severe UC to receive once-daily VidoCa (10, 30, or 45 mg) or placebo for 10 weeks (induction); patients with symptomatic remission were re-randomized to VidoCa 10, 30 mg, or placebo once-daily for an additional 40 weeks (maintenance).
Medicina (Kaunas)
November 2024
Department of Plastic and Reconstructive Surgery, Yeungnam University College of Medicine, 170, Hyeonchung-ro, Nam-gu, Daegu 42415, Republic of Korea.
: Postoperative recovery from general anesthesia is a multidimensional process, and patient-centered outcome assessment should be considered an important indicator of recovery quality. This study compared the effectiveness of intraoperative lidocaine and magnesium on postoperative recovery in nasal bone fracture surgery, using the quality of recovery-40 questionnaire (QoR-40) to assess recovery quality and pain intensity. : A total of 74 patients scheduled for elective closed reduction surgery for isolated nasal bone fracture were assigned to the intraoperative infusions of lidocaine or magnesium.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Department of Knee Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Background: The demand for total knee arthroplasty (TKA) is increasing, yet postoperative nausea and vomiting (PONV) significantly hinder patient recovery. Preoperative prophylactic administration of glucocorticoids can alleviate PONV, with betamethasone showing promising results in breast and cardiac surgeries. However, its efficacy in TKA patients remains unclear.
View Article and Find Full Text PDFAnesthesiology
December 2024
Department of Anesthesiology, The Third Xiangya Hospital, Central South University, No.138, Tongzipo Road, Yuelu District, Changsha, Hunan, China, 410013.
Background: Postoperative nausea and vomiting (PONV) are common complications after gynecological laparoscopic surgery. Pyridoxine has been recommended as a first-line drug to prevent and treat nausea and vomiting during pregnancy; however, its efficacy in preventing PONV remains unclear.
Methods: Patients of 18 to 65 years old, who received elective gynecological laparoscopic surgery under general anesthesia, were randomized into either the pyridoxine or control group.
Trials
December 2024
Department of Orthopedics, University Hospital of Southern Denmark, Kresten Philipsensvej 15, Aabenraa, 6200, Denmark.
Background: Hip fractures are a source of severe pain among the elderly population and pose challenges due to limited analgesic tolerance. Perioperative methadone has shown promise in our pilot study suggesting a safe dose of 0.10 mg/kg, prompting further investigation into its benefits for elderly hip fracture patients.
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