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Frontal Paraventricular Cysts: Refined Definitions and Outcomes.
AJNR Am J Neuroradiol
January 2025
From the Division of Neuroradiology, Department of Radiology (M.T.W., A.M., C.A.P.F.A., O.S, E.S.S.), and Department of Obstetrics and Gynecology (N.K.), Children's Hospital of Philadelphia, Philadelphia, PA, USA; Perelman School of Medicine (M.T.W., N.K., E.S.S.), Philadelphia, PA, USA; Division of Neuroradiology, Department of Radiology (C.A.P.F.A), Boston Children's Hospital, Boston, MA, USA; and Harvard Medical School (C.A.P.F.A), Boston, MA, USA.
Background And Purpose: Frontal paraventricular cystic changes have a varied etiology that includes connatal cysts, subependymal pseudocysts, necrosis, and enlarged perivascular spaces. These may be difficult to distinguish by neuroimaging and have a variety of associated prognoses. We aim to refine the neuroimaging definition of frontal horn cysts and correlate it with adverse clinical conditions.
View Article and Find Full Text PDFFetal intracranial hemorrhage in second trimester: An ominous finding even after a normal array.
Taiwan J Obstet Gynecol
January 2025
Genetics Lab of Longgang Maternity and Child Institute of Shantou University Medical College (Longgang District Maternity & Child Healthcare Hospital of Shenzhen City), Shenzhen, Guangdong, China. Electronic address:
Objective: This is a case report of a COL4A1 gene mutation which was confirmed by further genetic testing following anomalies observed in prenatal ultrasound and fetal brain magnetic resonance imaging (MRI).
Case Reports: The ultrasound examination of the patient revealed a mass in fetal left intracranial cavity. Repeated subsequent MRI detected an evolving mass in the left frontal parietal lobe.
[Management of a fetus suspected of differences of sex development (DSD).].
Gynecol Obstet Fertil Senol
January 2025
Department of Obstetrics and Gynaecology, Hôpital Saint Joseph, Marseille, France; Image2 center, Marseille, France. Electronic address:
The management of a fetus suspected of having a variation in genital development is a complex situation. In cases of complete discordance or an unusual appearance of the external genitalia (EG), management always begins with a diagnostic morphological ultrasound. This ultrasound aims to provide detailed imaging of the EG and internal genitalia (IG), focusing on identifying the presence of Müllerian derivatives and detecting any associated malformations.
View Article and Find Full Text PDFAssociation between cerebrospinal fluid levels of neuro-specific enolase after hypothermia alone and in combination with neurodevelopmental outcomes at age six years.
Early Hum Dev
January 2025
Division of Neonatology, Department of Maternal, Fetus and Perinatal Center, Saitama Children's Medical Center, Saitama, Japan.
Background: Hypoxic-ischemic encephalopathy (HIE) is still associated with death and sequelae including cerebral palsy and intellectual disability despite induced hypothermia. Biomarkers, as early predictive indicators of adverse outcomes, are lacking.
Aims: To investigate whether post-rewarming cerebrospinal fluid (CSF)-neuro-specific enolase (NSE) levels after hypothermia are associated with neurodevelopmental outcomes at age six years, alone or when combined with amplitude-integrated electroencephalography (aEEG) and brain magnetic resonance imaging (MRI), as neuroimaging and neurophysiological indicators, respectively.
A detailed spatiotemporal atlas of the white matter tracts for the fetal brain.
Proc Natl Acad Sci U S A
January 2025
Computational Radiology Laboratory, Boston Children's Hospital, Boston, MA 02115.
This study presents the construction of a comprehensive spatiotemporal atlas of white matter tracts in the fetal brain for every gestational week between 23 and 36 wk using diffusion MRI (dMRI). Our research leverages data collected from fetal MRI scans, capturing the dynamic changes in the brain's architecture and microstructure during this critical period. The atlas includes 60 distinct white matter tracts, including commissural, projection, and association fibers.
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