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SARS-CoV-2 surveillance in a hospital and control of an outbreak on a geriatric ward using whole genome sequencing.
Infect Prev Pract
September 2024
SARS-CoV-2 Sequencing Consortium, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Background: During the SARS-CoV-2 pandemic, dominant viral variants were repeatedly replaced by new variants with altered properties, frequently changing the dynamics of the infection event, as well as the effectiveness of vaccines and therapeutics. SARS-CoV-2 variant monitoring by whole genome sequencing was established at the University Medical Center Mainz, Germany to support patient management during the pandemic.
Methods: SARS-CoV-2 RNA samples from the University Medical Center were analysed weekly with whole genome sequencing.
Trauma patients with metastatic cancer undergoing emergent surgery: A matched cohort analysis.
Surg Open Sci
August 2024
University of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, Orange, CA, USA.
Background: There is a paucity of literature guiding trauma surgeons in the care of patients with active metastatic cancer (MC). Even less is known regarding outcomes for MC patients requiring emergent surgery after trauma. We hypothesized that trauma patients with active Metastatic Cancer (MC) have an increased mortality rate and undergo increased rates of withdrawal of care (WoC) within 72-hours following emergent operations, compared to similarly matched patients without MC.
View Article and Find Full Text PDFSevere pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report.
BMC Pregnancy Childbirth
January 2025
Department of Intensive Care Medicine, Army Medical Center of PLA, No. 10 Changjiang Road, Yuzhong District, Chongqing, 400010, People's Republic of China.
Background: Pregnancy-associated atypical hemolytic uremic syndrome (aHUS) is a form of thrombotic microangiopathy (TMA) caused by uncontrolled activation of the complement system during pregnancy or the postpartum period. In the intensive care unit, aHUS must be differentiated from sepsis-related multiple organ dysfunction, thrombotic thrombocytopenic purpura (TTP), hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome. Early recognition of aHUS is critical for effective treatment and improved prognosis.
View Article and Find Full Text PDFRobot-assisted PFNA surgery improves clinical outcomes in the treatment of unstable femoral intertrochanteric fractures in elderly patients compared with traditional PFNA surgery.
Sci Rep
January 2025
Derpartment of Orthopedics, Shaoguan First People's Hospital Affiliated to Guangdong Medical University, Shaoguan City, 512000, Guangdong, China.
To assess the clinical outcomes of robot-assisted proximal femoral nail antirotation (PFNA) surgery in elderly patients with unstable femoral intertrochanteric fractures (UFIFs). 151 patients who underwent UFIF and PFNA surgery between January 2020 and May 2024 were analyzed retrospectively. Of these, 78 patients were treated with traditional PFNA surgery (control group), and 73 patients were treated with robot-assisted PFNA surgery (observation group).
View Article and Find Full Text PDFIndications for and limitations of laparoscopic anatomical liver resection: assessment of postoperative complications stratified by complexity of liver resection.
Surg Endosc
January 2025
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, 2-13-22 Miyakojima-Hondori, Miyakojima-Ku, Osaka, 534-0021, Japan.
Background: Although complex anatomical liver resections are more often being performed laparoscopically, the short-term outcomes following laparoscopic anatomical liver resection (LALR), its optimal indications, and limitations remain unclear. This study aimed to clarify the indications for and limitations of LALR by assessing the short-term outcomes.
Methods: This retrospective study included 233 patients who underwent LALR.
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