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Pediatric macular disorders are a diverse group of inherited retinal diseases characterized by central vision loss due to dysfunction and degeneration of the macula, the region of the retina responsible for high-acuity vision. Common disorders in this category include Stargardt disease, Best vitelliform macular dystrophy, and X-linked retinoschisis. These conditions often manifest during childhood or adolescence, with symptoms such as progressive central vision loss, photophobia, and difficulty with fine visual tasks.

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Adaptive functioning and relationship to visual behavior in children with cerebral/cortical visual impairment.

J AAPOS

January 2025

Keck School of Medicine of USC, Los Angeles, California; Division of Ophthalmology, Children's Hospital Los Angeles, Los Angeles, California. Electronic address:

Background: Cerebral/cortical visual impairment (CVI) is a leading cause of pediatric visual impairment in developed countries and is associated with neurologic conditions that may impair adaptive functioning or skills required to perform everyday tasks (eg, communication, socialization, and daily living skills). Adaptive behavior in children with CVI has not been systematically studied, and the relationship between visual function and adaptive function in CVI is unknown.

Methods: We prospectively recruited 49 children with CVI (mean age, 4 ± 3 years).

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Implementation of artificial intelligence approaches in oncology clinical trials: A systematic review.

Artif Intell Med

January 2025

Department of Chemistry, School of Sciences & Engineering, The American University in Cairo, AUC Avenue, P. O. Box 74, New Cairo 11835, Egypt. Electronic address:

Introduction: There is a growing interest in leveraging artificial intelligence (AI) technologies to enhance various aspects of clinical trials. The goal of this systematic review is to assess the impact of implementing AI approaches on different aspects of oncology clinical trials.

Methods: Pertinent keywords were used to find relevant articles published in PubMed, Scopus, and Google Scholar databases, which described the clinical application of AI approaches.

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Introduction: Diabetic retinopathy grading plays a vital role in the diagnosis and treatment of patients. In practice, this task mainly relies on manual inspection using human visual system. However, the human visual system-based screening process is labor-intensive, time-consuming, and error-prone.

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Improvement of stereopsis following strabismus surgery in adults: a retrospective analysis.

Can J Ophthalmol

January 2025

Department of Ophthalmology, Sheba Medical Center of Israel, Israel; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objective: Adults who undergo strabismus surgery, in addition to cosmesis, could benefit from improved stereopsis. This improvement is associated with the performance of motor skill tasks in young adults; they reduce the risk of tripping or falling during everyday locomotion and improve reading efficiency. This study aimed to assess stereopsis level after strabismus surgery in adults who underwent strabismus surgery for any reason.

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