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Development and validation of an integrated model for the diagnosis of liver cirrhosis with portal vein thrombosis combined with endoscopic characters and blood biochemistry data: a retrospective propensity score matching (PSM) cohort study.
Ann Med
December 2025
Endoscopic Diagnosis and Treatment Center, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Background: Liver cirrhosis complicated by portal vein thrombosis (PVT) is a fatal complication with no specific manifestations but often misdiagnosed, it crucially increases the mortality worldwide. This study aimed to identify risk factors and establish a predictive model for diagnosis of venous thrombosis clinical by routine blood tests and endoscopic characteristics.
Methods: Patients from Gansu Provincial Hospital from October 2019 to December 2023 were enrolled.
Machine learning web application for predicting varicose veins utilizing global prevalence data.
Phlebology
January 2025
Department of Vascular Surgery, University Hospital Leipzig, Leipzig, Germany.
Aim: This study aimed to develop a web-based machine learning (ML) model to predict the lifetime likelihood of developing varicose veins using global disease prevalence data.
Methods: We utilized data from a systematic review, registered under PROSPERO (CRD42021279513), which included 81 studies on varicose vein prevalence across various geographic regions. The data used to build the ML model included disease prevalence as the outcome (%), along with the following predictors: mean age, gender distribution (%), mean body mass index (BMI) of the study cohort, and the mean gravity field of the study region (mGal), representing variations in Earth's underground mass distribution that influence blood and fluid redistribution in the human body, affecting disease prevalence.
Machine learning prediction of hepatic encephalopathy for long-term survival after transjugular intrahepatic portosystemic shunt in acute variceal bleeding.
World J Gastroenterol
January 2025
Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510151, Guangdong Province, China.
Background: Transjugular intrahepatic portosystemic shunt (TIPS) is an effective intervention for managing complications of portal hypertension, particularly acute variceal bleeding (AVB). While effective in reducing portal pressure and preventing rebleeding, TIPS is associated with a considerable risk of overt hepatic encephalopathy (OHE), a complication that significantly elevates mortality rates.
Aim: To develop a machine learning (ML) model to predict OHE occurrence post-TIPS in patients with AVB using a 5-year dataset.
Short and Mid-term Outcome of Radiofrequency Ablation without Concomitant Phlebectomy/Sclerotherapy for Tributary Varicose Veins.
Ann Vasc Dis
January 2025
Department of Cardiovascular Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
Endovenous surgery in the treatment of varicose veins generally consists of laser or radiofrequency ablation (RFA) as endovenous thermal ablation (ETA) with a phlebectomy or foam sclerotherapy of tributary varicose veins to improve symptomatic or cosmetic problems. Nevertheless, the efficacy of their concomitant treatments is still controversial for a decade. In the guidelines of the Japanese Society of Phlebology, concomitant phlebectomy of tributary varicose veins with ETA is described that it is not recommended officially.
View Article and Find Full Text PDFGlycocalyx disruption, endothelial dysfunction and vascular remodeling as underlying mechanisms and treatment targets of chronic venous disease.
Int Angiol
December 2024
Vascular Surgery Research Laboratories, Division of Vascular and Endovascular Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA -
The glycocalyx is an essential structural and functional component of endothelial cells. Extensive hemodynamic changes cause endothelial glycocalyx disruption and vascular dysfunction, leading to multiple arterial and venous disorders. Chronic venous disease (CVD) is a common disorder of the lower extremities with major health and socio-economic implications, but complex pathophysiology.
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