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Pharmacological Treatment of Neonatal and Juvenile Mice to Study Spermatogenesis. | LitMetric

Pharmacological Treatment of Neonatal and Juvenile Mice to Study Spermatogenesis.

Methods Mol Biol

Department of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, Greenville, NC, USA.

Published: June 2023

AI Article Synopsis

Article Abstract

The delivery, to newborn and juvenile mice, of drugs and other compounds that manipulate the physiology or cellular/molecular state -e.g., by activating or inhibiting signaling pathways) is a powerful, yet underutilized approach to studying spermatogenesis. Here, we provide detailed protocols we have optimized in our laboratory for safely and effectively feeding and injecting mice and discuss troubleshooting approaches.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473193PMC
http://dx.doi.org/10.1007/978-1-0716-3139-3_13DOI Listing

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