Gallbladder carcinosarcoma invading the common bile duct: A case report.

Asian J Surg

Department of General Surgery, Jinzhou Medical University Postgraduate Training Base (Jinzhou Central Hospital), Jinzhou City, Liaoning Province, China. Electronic address:

Published: October 2023

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http://dx.doi.org/10.1016/j.asjsur.2023.05.058DOI Listing

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Article Synopsis
  • - A 68-year-old woman was admitted to the hospital with acute cholangitis, and imaging tests showed issues like dilated common bile duct and a tumor in the gallbladder.
  • - The patient was diagnosed with pancreaticobiliary maljunction causing biliary dilation and gallbladder cancer, leading to surgery for liver and bile duct reconstruction.
  • - Pathological analysis revealed that the gallbladder tumor contained sarcoma, and the thickened wall had adenocarcinoma, resulting in a diagnosis of gallbladder carcinosarcoma.
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Article Synopsis
  • Gallbladder cancers (GBC) are rare but deadly tumors that are often diagnosed incidentally after gallbladder removal surgery due to unforeseen findings during lab examinations.
  • The study focused on the Kurdistan region, specifically Sulaymaniyah, analyzing data from 8,315 patients who underwent cholecystectomy between 2017 and 2021, revealing that GBC diagnosis mainly occurs in older individuals, with many being female.
  • Out of the total cases, 46 were identified as gallbladder cancer, with a noteworthy prevalence of acute cholecystitis in 10.5% of patients, highlighting a significant link between age, gender, and GBC findings.
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Gallbladder carcinosarcoma with a poor prognosis: A case report.

World J Clin Cases

April 2024

Department of Hepatobiliary Surgery, Suining Central Hospital, Suining 629000, Sichuan Province, China.

Background: Carcinosarcoma of the gallbladder is a rare malignant tumor with a very poor prognosis. To date, only approximately 100 patients have been reported in the English literature. The prognosis of this tumor type is poor, the preoperative diagnosis is difficult, and there is a possibility of a misdiagnosis.

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Background: Carcinosarcoma of the gallbladder (CSGB) is an uncommon malignancy, and limited literature is available on its clinicopathological features, prognosis, and treatment options.

Methods: Using the SEER database, we selected 7634 gallbladder adenocarcinoma patients (diagnosed from 2004 to 2015) and 58 carcinosarcoma of the gallbladder patients (diagnosed from 1988 to 2019) based on predetermined criteria. We compared the overall survival (OS) and cancer-specific survival (CSS) before and after propensity score matching in two groups.

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