Fixed Sunlight Eruption: A Series of 13 Cases in Bogotá, Columbia.

Actas Dermosifiliogr

Fundación Santafé de Bogotá, Bogotá, Colombia.

Published: March 2024

AI Article Synopsis

  • * A study involved 13 patients, predominantly women, aged 28 to 56, who experienced these eruptions at a dermatology referral hospital in Bogotá, Colombia.
  • * The lesions appeared in specific areas of the body and were confirmed through photoprovocation and histopathology, suggesting a potential link to fixed drug eruptions, although they might represent a different condition with a similar cause.

Article Abstract

Few reports describing an association between UV radiation and fixed skin eruptions have been published since 1975. These reactions have received various names, including fixed sunlight eruption, fixed exanthema due to UV radiation, and broad-spectrum abnormal localized photosensitivity syndrome. We present a series of 13 patients (4 men [30.8%] and 9 women [69.2%]) aged between 28 and 56 years who were evaluated for fixed eruptions induced by UV radiation at a dermatology referral hospital in Bogotá, Colombia. The lesions were located on the inner thighs, buttocks, popliteal region, anterior and posterior axilla, and dorsum of the feet. Photoprovocation reproduced lesions in all the affected areas, and histopathology showed changes similar to those seen in fixed drug eruptions. While these UV-provoked reactions may be a type of fixed skin eruption, we cannot rule out that they may also be a distinct condition that simply shares a pathogenic mechanism with fixed eruptions.

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Source
http://dx.doi.org/10.1016/j.ad.2023.04.030DOI Listing

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