AI Article Synopsis
- The study investigates a natural outbreak of carp edema virus disease (CEVD) in koi carp, focusing on various aspects such as clinical symptoms, pathology, immune responses, and viral detection methods.
- Findings revealed significant changes in white blood cell counts, with increased monocytes and decreased lymphocytes in affected fish, alongside heightened phagocytic activity.
- Additionally, the research identifies new histopathological damage in the pancreatic tissue of diseased koi carp, contributing to a deeper understanding of CEVD pathology.
Article Abstract
In the present study, we describe a natural outbreak of carp edema virus disease (CEVD) in koi carp, concentrating on clinical manifestation, gross and microscopic pathology, immunological parameters, viral diagnostics, and phylogenetic analysis. Examination of white blood cell parameters showed increased monocyte and decreased lymphocyte counts in CEV-affected fish compared to healthy control fish. Regarding immune system functioning, the present work shows, for the first time, enhanced phagocytic activity in CEV-affected fish. Respiratory burst of phagocytes was strongly increased in diseased fish, the increase being attributed to an increased phagocyte count rather than enhancement of their metabolic activity. The present work also newly shows histopathological changes in the pancreatic tissue of diseased koi.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221307 | PMC |
| http://dx.doi.org/10.3390/v15051044 | DOI Listing |
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