The COVID-19 pandemic has dramatically impacted the global healthcare system, revealing critical gaps in our capacity to provide efficient and effective care to patients, particularly those with chronic diseases [...].
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http://dx.doi.org/10.3390/jpm13050722 | DOI Listing |
Evid Based Nurs
January 2025
University of Massachusetts Boston - College of Nursing and Health Sciences, Boston, Massachusetts, USA.
BMJ Open
January 2025
O'Donnell School of Public Health, UT Southwestern Medical Center, Dallas, Texas, USA
Introduction: Linking patients living with chronic, diet-related diseases and food insecurity to charitable food assistance, medically tailored groceries (MTGs) and food resource coaching may empower patients to better manage their health in a way that is economically sustainable. This protocol paper describes the implementation of a study evaluating MTGs and food resource coaching in a food pantry setting.
Methods And Analysis: A randomised controlled trial whereby patients of a safety-net health centre will be screened for The Emergency Food Assistance Program (TEFAP) and study eligibility.
Int Nurs Rev
March 2025
College of Nursing, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Aim: To explore the effect of violence exposure on altruistic behavior and grit among emergency nurses in 103-bed emergency departments in rural hospitals in Egypt.
Background: Workplace violence is a pervasive issue in emergency departments. Nurses in rural hospitals, facing limited resources and isolation, may be even more vulnerable to the adverse effects of workplace violence.
ACS Appl Mater Interfaces
January 2025
School of Biological Sciences, University of Hong Kong, Pokfulam, Hong Kong 999077, China.
Ovarian cancer is the leading cause of death among all gynecological malignancies, and drug resistance renders the current chemotherapy agents ineffective for patients with advanced metastatic tumors. We report an effective treatment strategy for targeting metastatic ovarian cancer involving a nanoformulation (Bola/IM)─bola-amphiphilic dendrimer (Bola)-encapsulated imatinib (IM)─to target the critical mediator of ovarian cancer stem cells (CSCs) CD117 (c-Kit). Bola/IM offered significantly more effective targeting of CSCs compared to IM alone, through a novel and tumor-specific β-catenin/HRP2 axis, allowing potent inhibition of cancer cell survival, stemness, and metastasis in metastatic and drug-resistant ovarian cancer cells.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
CNR Institute of Neuroscience, Vedano al Lambro, Italy.
Background: We recently demonstrated that large extracellular vesicles (EVs) released by Aβ-loaded microglia and carrying Aβ (Aβ-EVs) propagate synaptic dysfunction in the mouse brain by moving at the axon surface (Gabrielli et al., Brain, 2022; Falcicchia et al., Brain Commun, 2023).
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