The study of gene expression regulation raises the challenge of developing bioinformatics tools and algorithms, demanding data integration [...].
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218204 | PMC |
| http://dx.doi.org/10.3390/ijms24108774 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Low-added sugar dietary intervention study to mitigate glucose intolerance and improve body composition in adults with cystic fibrosis: a protocol of a double-blind, randomised study.
BMJ Open
December 2024
Division of Endocrinology, Metabolism, and Lipids; Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Introduction: People with cystic fibrosis (PwCF) are at high risk for developing cystic fibrosis (CF)-related diabetes (CFRD), which worsens morbidity and mortality. Although the pathological events leading to the development of CFRD are complex and not completely understood, dietary factors may play a role. For example, habitual intake of dietary added sugar (i.
View Article and Find Full Text PDFIdentification of key factors related to digital health observational study adherence and retention by data-driven approaches: an exploratory secondary analysis of two prospective longitudinal studies.
Lancet Digit Health
January 2025
Biomedical Engineering Department, Duke University, Durham, NC, USA; Biostatistics and Bioinformatics Department, Duke University, Durham, NC, USA. Electronic address:
Background: Longitudinal digital health studies combine passively collected information from digital devices, such as commercial wearable devices, and actively contributed data, such as surveys, from participants. Although the use of smartphones and access to the internet supports the development of these studies, challenges exist in collecting representative data due to low adherence and retention. We aimed to identify key factors related to adherence and retention in digital health studies and develop a methodology to identify factors that are associated with and might affect study participant engagement.
View Article and Find Full Text PDFIsolation and Identification of Brain Tissue Extracellular Vesicles for Translational Proteomics.
Methods Mol Biol
December 2024
Department of Biochemistry, Purdue University, West Lafayette, IN, USA.
Extracellular vesicles (EVs) are small membrane-bound structures that play important roles in intercellular communication and the transfer of biomolecules between cells. EVs have become a topic of interest for research in translational proteomics for disease biomarker discovery due to their ability to reflect changes in the cellular proteome, including diseases affecting the brain. Utilizing the proteome analysis of EVs to its fullest potential requires proper isolation and purity.
View Article and Find Full Text PDFHuman genetics and genomics as a unifying factor for harmony and progress in Africa: a report from the 12 African Society of Human Genetics meeting in Bamako, Mali.
Pan Afr Med J
December 2024
Faculté de Médecine et d'Odontostomatologie, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Since its inception in 2003, the African Society of Human Genetics (AfSHG) has been central to the promotion of genetics research on the continent, and facilitated the networking of African researchers within Africa and abroad, thereby significantly contributing to the career development of African geneticists. The continuation of these accomplishments was stimulated by the 12 international conference of AfSHG held jointly with the 1 Congress of the Malian Society of Human Genetics (MSHG) in Bamako, Mali from September 18 to 21 2019. The main theme of the conference was "Human Genetics and Genomics as a Unifying Factor for Harmony and Progress in Africa".
View Article and Find Full Text PDFThis paper describes the unique values of, challenges within, and opportunities presented by embedded ELSI ethnography. Drawing from our six-year embedded ELSI study of the WISDOM (Women Informed to Screen Depending on Measures of Risk) trial, we present three examples of the variable ways we engaged with the WISDOM trial's scientific team. WISDOM is a preference-sensitive, pragmatic, randomized controlled trial of risk-based breast cancer screening informed by genomics.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!