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Chemical Composition of the Leaf Essential Oil and Analysis of Its Antioxidant, Enzyme Inhibitory and Antibacterial Activities. | LitMetric

AI Article Synopsis

  • - The species in question are part of the Lauraceae family, widely used for spices and noted for their cosmetic and medicinal benefits.
  • - A study of the essential oil from (Burm. f.) J. Presl revealed it contains significant amounts of linalool and caryophyllene, along with other compounds like benzyl benzoate and eugenol.
  • - The essential oil demonstrated strong antioxidant activity and showed potential for inhibiting enzymes related to diabetes, as well as exhibiting antibacterial properties against various bacteria.

Article Abstract

species are a group of plants belonging to the Lauraceae family. These plants are predominantly used as spices in various food preparations and other culinary purposes. Furthermore, these plants are attributed to having cosmetic and pharmacological potential. (Burm. f.) J. Presl is an underexplored plant in the genus. The present study evaluated the chemical composition by a GC-MS analysis and antioxidant properties of the essential oil from (CMEO). Further, the pharmacological effects were determined as radical quenching, enzyme inhibition and antibacterial activity. The results of the GC-MS analysis indicated the presence of 38.26 % of linalool and 12.43% of caryophyllene in the essential oil. Furthermore, the benzyl benzoate (9.60%), eugenol (8.75%), cinnamaldehyde (7.01%) and humulene (5.32%) were also present in the essential oil. The antioxidant activity was indicated by radical quenching properties, ferric-reducing potential and lipid peroxidation inhibition ex vivo. Further, the enzyme-inhibitory potential was confirmed against the enzymes involved in diabetes and diabetic complications. The results also indicated the antibacterial activity of these essential oils against different Gram-positive and Gram-negative bacteria. The disc diffusion method and minimum inhibitory concentration analysis revealed a higher antibacterial potential for essential oil. Overall, the results identified the predominant chemical compounds of essential oil and its biological and pharmacological effects.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215355PMC
http://dx.doi.org/10.3390/antibiotics12050940DOI Listing

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