AI Article Synopsis

  • The rise of antibiotic-resistant bacteria poses a major challenge for medical treatments, as misuse of conventional antibiotics leads to increased resistance and fewer effective options in the future.
  • The article highlights the urgency of addressing antimicrobial resistance (AMR) through the discovery of new antibacterial compounds and innovative drug delivery methods compared to traditional systems.
  • It also discusses AMR-related infections and emphasizes the need for advanced antimicrobial delivery devices, particularly focusing on smart delivery systems for antibiotics.

Article Abstract

Globally, the increase of pathogenic bacteria with antibiotic-resistant characteristics has become a critical challenge in medical treatment. The misuse of conventional antibiotics to treat an infectious disease often results in increased resistance and a scarcity of effective antimicrobials to be used in the future against the organisms. Here, we discuss the rise of antimicrobial resistance (AMR) and the need to combat it through the discovery of new synthetic or naturally occurring antibacterial compounds, as well as insights into the application of various drug delivery approaches delivered via various routes compared to conventional delivery systems. AMR-related infectious diseases are also discussed, as is the efficiency of various delivery systems. Future considerations in developing highly effective antimicrobial delivery devices to address antibiotic resistance are also presented here, especially on the smart delivery system of antibiotics.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10215767PMC
http://dx.doi.org/10.3390/antibiotics12050822DOI Listing

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