Multiphase flows involving granular materials are complex and prone to pattern formation caused by competing mechanical and hydrodynamic interactions. Here we study the interplay between granular bulldozing and the stabilising effect of viscous pressure gradients in the invading fluid. Injection of aqueous solutions into layers of dry, hydrophobic grains represent a viscously stable scenario where we observe a transition from growth of a single frictional finger to simultaneous growth of multiple fingers as viscous forces are increased. The pattern is made more compact by the internal viscous pressure gradient, ultimately resulting in a fully stabilised front of frictional fingers advancing as a radial spoke pattern.
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http://dx.doi.org/10.1038/s41467-023-38648-6 | DOI Listing |
Gels
November 2024
School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
This study presents the development of thiol-maleimide/thiol-thiol double self-crosslinking hyaluronic acid-based (HA) hydrogels for use as dermal fillers. Hyaluronic acid with varying degrees of maleimide substitution (10%, 20%, and 30%) was synthesized and characterized, and HA hydrogels were fabricated using two molecular weights of four-arm polyethylene glycol (PEG10K/20K)-thiol as crosslinkers. The six resulting HA hydrogels demonstrated solid-like behavior with distinct physical and rheological properties.
View Article and Find Full Text PDFMethods Mol Biol
December 2024
Centre de Biologie Structurale, Université de Montpellier, CNRS, INSERM, Montpellier, France.
The bacterial flagellar motor (BFM) is a rotary molecular machine that drives critical bacterial processes including motility, chemotaxis, biofilm formation, and infection. For over two decades, the bead assay, which measures the rotation of a microparticle attached to the flagellum of a surface-attached bacterium, has been instrumental in deciphering the motor's biophysical mechanisms. This technique has not only quantified the rotational speed and frequency of directional switching as a function of the viscous load on the flagellum but has also revealed the BFM's capacity for mechanosensitive speed modulation, adapting to environmental conditions.
View Article and Find Full Text PDFMath Biosci
December 2024
Department of Chemical Engineering, Indian Institute of Technology Bombay (IITB), 400076 Mumbai, India.
Cell migration regulates central life processes including embryonic development, tissue regeneration, and tumor invasion. To establish the direction of migration, cells follow exogenous cues. Durotaxis, the directed cell migration towards elastic stiffness gradients, is the classical example of mechanical taxis.
View Article and Find Full Text PDFWater Res
December 2024
BRGM (French Geological Survey), Orléans 45060, France.
Polymer solution injection has emerged as a promising method for the remediation of NAPL (non-aqueous phase liquids)-contaminated aquifers. This technique enhances recovery efficiency by modifying viscous forces, stabilizing the displacement front, and minimizing channeling effects. However, there remains a significant gap in understanding the behavior of polymer solutions, particularly those with different molecular weights (MW), for mobilizing DNAPL (dense non-aqueous phase liquids) trapped in heterogeneous aquifers, especially within low-permeability layers.
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2024
Department of Mechanical Engineering, Baylor University, One Bear Place #97356, Waco, 76798, TX, United States. Electronic address:
This study reveals how drops impacting thin liquid films leave behind radial microbubble trains - here defined as large-area microbubbles (LAMs) - over a region comparable to the maximal surface coverage of the spreading phase. Using a thin, minimally compliant viscous oil film, the trapped bubbles are immobilized and quantified via high-speed imaging techniques across varying drop velocities and surface inclinations. The setup enables the characterization of microbubble entrainment (e.
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