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An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum. | LitMetric
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An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum.

Phool Iqbal Aamir Shahzad Zubair Shahid Firdous Ghori Halima Elomri Dina Soliman

Clin Case Rep

Medical Oncology-Hematology Department National Centre for Cancer Care and Research (NCCCR) Hamad Medical Corporation (HMC) Doha Qatar.

Published: May 2023

Chronic myeloid leukemia (CML) is a myeloproliferative disorder due to translocation between chromosomes (9, 22), known as the "Philadelphia chromosome." In 2016, the World health organization (WHO) introduced a new clinical entity of de novo acute myeloid leukemia (AML). Both diseases share some commonalities, therefore, create a challenge to diagnose.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206018PMC
http://dx.doi.org/10.1002/ccr3.5908DOI Listing

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