AI Article Synopsis
- Lung cancer ranks as the top cause of cancer-related deaths globally, making accurate biopsies essential for diagnosis and analysis.
- Guidelines suggest using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for staging lung cancer, but its limited sample size may hinder the diagnosis of rare thoracic tumors.
- A new technique called transbronchial mediastinal cryobiopsy shows promise in improving diagnostic outcomes, as demonstrated by a case where it successfully diagnosed a rare thoracic tumor alongside EBUS-TBNA.
Article Abstract
Lung cancer is the leading cause of deaths from malignant neoplasms worldwide, and a satisfactory biopsy that allows for histological and other analyses is critical for its diagnosis. Guidelines have recommended endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) as the reference standard for the staging of lung cancer. However, the relatively limited sample volume retrieved by needle aspiration might restrict the diagnostic capacity of EBUS-TBNA in other uncommon thoracic tumors. Transbronchial mediastinal cryobiopsy is a recently developed sampling strategy for mediastinal lesions, which demonstrates added diagnostic value to conventional needle aspiration. Here, we present a case of thoracic SMARCA4-deficient undifferentiated tumor successfully diagnosed by mediastinal cryobiopsy additional to EBUS-TBNA.
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| http://dx.doi.org/10.1159/000529986 | DOI Listing |
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