Clathrates are open crystals in which molecules are arranged in a hierarchy of polyhedral cages that encapsulate guest molecules and ions. As well as holding fundamental interest, molecular clathrates serve practical purposes, such as for gas storage, and their colloidal counterparts also appear promising for host-guest applications. Here using Monte Carlo simulations, we report the entropy-driven self-assembly of hard truncated triangular bipyramids into seven different host-guest colloidal clathrate crystals with unit cells ranging from 84 to 364 particles. The structures consist of cages that are either empty or occupied by guest particles, which can be different from or identical to the host particles. The simulations point to crystallization occurring through the compartmentalization of entropy between low- and high-entropy subsystems for the host and the guest particles, respectively. We use entropic bonding theory to design host-guest colloidal clathrates with explicit interparticle attraction, providing a route to realize such systems in the laboratory.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41557-023-01200-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A β-cyclodextrin-based supramolecular photonic crystal hydrogel biosensor with macroporous structures for naked-eye visual detection of cholesterol.
Carbohydr Polym
March 2025
College of Chemistry and Environment, Southwest Minzu University, Chengdu, Sichuan 610225, China; Key Laboratory of Fundamental Chemistry of the State Ethnic Commission, College of Chemistry and Environment, Southwest Minzu University, Chengdu, Sichuan 610225, China. Electronic address:
Cholesterol (CHO) is an essential lipid in cell membranes and a precursor for vital living substances. Abnormal CHO levels can cause cardiovascular diseases. Therefore, simple and accurate monitoring of CHO levels is crucial for early diagnosis and effective management of cardiovascular diseases.
View Article and Find Full Text PDFDevelopment of hyaluronic acid/β-cyclodextrin semi-interpenetrating network hydrogels for prolonged delivery of water-soluble sunitinib malate.
Int J Pharm
January 2025
UCL School of Pharmacy, University College London, 29 - 39 Brunswick Square, London WC1N 1AX, UK. Electronic address:
Sunitinib malate (SUM), widely used in cancer treatment for its anti-VEGF properties, has also been explored for ocular neovascular diseases. For ocular applications, sustained drug release is essential to reduce dosing frequency. Hyaluronic acid (HA)-based hydrogels are commonly used for controlled drug delivery, but their hydrophilicity leads to rapid drug diffusion, especially for water-soluble drugs like SUM.
View Article and Find Full Text PDFNovel cocktail therapy based on multifunctional supramolecular hydrogel targeting immune-angiogenesis-nerve network for enhanced diabetic wound healing.
J Nanobiotechnology
December 2024
Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Diabetes-associated chronic skin wounds present a formidable challenge due to inadequate angiogenesis and nerve regeneration during the healing process. In the present study, we introduce a groundbreaking approach in the form of a novel cocktail therapy utilizing a multifunctional supramolecular hydrogel. Formulated through the photo-crosslinking of gelatinized aromatic residues and β-cyclodextrin (β-CD), this injectable hydrogel fosters weak host-guest interactions, offering a promising solution.
View Article and Find Full Text PDFReconfiguring Alginate-Based Supra-amphiphiles via Redox-Responsive Pickering Emulsions for Enhancing Pesticide Droplet Retention.
ACS Appl Mater Interfaces
December 2024
School of Chemistry and Chemical Engineering, Hainan University, 58 Renmin Road, Haikou, Hainan Province 570228, China.
In view of the micro/nanostructure tunability of colloid particles, they acted as agrichemical delivery systems. Herein, supra-amphiphilic colloids were fabricated using a host-guest interfacial recognition-architected emulsion template strategy and controlled their agricultural interfacial interactions with the superhydrophobic target surface. Interestingly, the supramolecular interfacial system possessed redox-stimulated molecular reconfigurability by regulating aggregation/disaggregation behaviors.
View Article and Find Full Text PDFGuest modulating the photoactivity of a titanium-oxide cage.
Chem Sci
December 2024
Key Lab for Colloid and Interface Science of Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University Jinan 250100 China
Two host-guest Ti-oxide clusters, Ti(NH) and TiCs, were synthesized and thoroughly characterized. They possess a rarely seen biloculate structure that encapsulates two NH and Cs guests, respectively. Interestingly, alkali metal cations can exchange places with NH .
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!