AI Article Synopsis
- - The study investigates the risk factors and incidence of prolonged mechanical ventilation (PMV) after lung transplantation (LT) in patients at Bichat Claude Bernard Hospital from 2016 to 2020, finding that 28% required PMV for an average of 34 days.
- - Significant independent risk factors for PMV include higher body mass index (BMI), diabetes in the recipient, ECMO support during surgery, and receiving more than 5 red blood cell transfusions.
- - One-year survival rates show a concerning increase in mortality for patients on PMV (44%) compared to those without it (15%), highlighting the need to consider preoperative risk factors like BMI and diabetes in recipient selection.
Article Abstract
Background: Risk factors and the incidence of prolonged mechanical ventilation (PMV) after lung transplantation (LT) have been poorly described. The study assessed predictive factors of PMV after LT.
Methods: This observational, retrospective, monocentric study included all patients who received LT in Bichat Claude Bernard Hospital between January 2016 and December 2020. PMV was defined as a duration of MV > 14 days. Independent risk factors for PMV were studied using multivariate analysis. One-year survival depending on PMV was studied using Kaplan Meier and log-rank tests. A value <0.05 was defined as significant.
Results: 224 LT recipients were analysed. 64 (28%) of them received PMV for a median duration of 34 [26-52] days versus 2 [1-3] days without PMV. Independent risk factors for PMV were higher body mass index (BMI) ( = 0.031), diabetes mellitus of the recipient ( = 0.039), ECMO support during surgery ( = 0.029) and intraoperative transfusion >5 red blood cell units ( < 0.001). Increased mortality rates were observed at one-year in recipients who received PMV (44% versus 15%, < 0.001).
Conclusion: PMV was associated with increased morbidity and mortality one-year after LT. Preoperative risk factors (BMI and diabetes mellitus) must be considered when selecting and conditioning the recipients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203407 | PMC |
| http://dx.doi.org/10.3389/fmed.2023.1160621 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Investigation of Sliding Mode Control in the Nonlinear Modeling of Cordless Jigsaws.
Sensors (Basel)
January 2025
Department of Electrical Engineering and Mechatronics, Faculty of Engineering, Vehicles and Mechatronics Institute, University of Debrecen, Ótemető Str. 2-4., H-4028 Debrecen, Hungary.
The aim of this paper was to reduce the current spikes in battery-powered saw motors by designing and implementing a sliding mode model-following adaptive controller. The proposed controller reduces overcurrent consumption, improves system energy efficiency, and effectively maximizes battery runtime, especially under high-load conditions. By applying nonlinear compensation techniques, the controller can ensure smooth motor operation, reduce mechanical stress, and prolong tool life.
View Article and Find Full Text PDFImpact of Multidrug-Resistant Bacteria in a Cohort of COVID-19 Critically Ill Patients: Data from a Prospective Observational Study Conducted in a High-Antimicrobial-Resistance-Prevalence Center.
J Clin Med
January 2025
Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.
: Bacterial superinfections are common complications during viral infections, but the impact of multidrug-resistant (MDR) pathogens in critically ill patients affected by coronavirus disease 2019 (COVID-19) is still debated. : This is an observational, monocentric, and prospective study designed to investigate the incidence, risk factors, and outcomes of MDR bacterial superinfections in COVID-19 patients admitted to the intensive care unit (ICU). : A high incidence of superinfections (66%, 159/241) was observed: ventilator-associated pneumonia (VAP) (65%, 104/159) and bloodstream infection (BSI, 32%, 51/159) were the most common.
View Article and Find Full Text PDFStudy of the Influence of Desert Sand-Mineral Admixture on the Abrasion Resistance of Concrete.
Materials (Basel)
January 2025
College of Water Conservancy & Architectural Engineering, Shihezi University, Shihezi 832000, China.
The incorporation of desert sand-mineral admixture improves the abrasion resistance of concrete. To prolong the service life of assembled concrete channels and mitigate the depletion of river sand resources, the effects of fly ash (FA), silica fume (SF), desert sand (DS), and basalt fiber (BF) on the mechanical properties and the abrasion resistance of concrete were examined, alongside an analysis of their microstructures to elucidate the underlying mechanisms of influence. The results indicated that the abrasion resistance strength of concrete mixed with 10% FA and 0.
View Article and Find Full Text PDFMicrostructure and Thermal Cyclic Behavior of FeNiCoAlTaB High-Entropy Alloy.
Materials (Basel)
January 2025
Department of Materials Science and Engineering, National Taiwan University, Taipei 10617, Taiwan.
This study investigates the grain morphology, microstructure, magnetic properties and shape memory properties of an FeNiCoAlTaB (at%) high-entropy alloy (HEA) cold-rolled to 98%. The EBSD results show that the texture intensities of the samples annealed at 1300 °C for 0.5 or 1 h are 2.
View Article and Find Full Text PDFInsights into the Corrosion Inhibition Performance of Plant Extracts of Different Genera in the Asteraceae Family for Q235 Steel in HSO Medium.
Int J Mol Sci
January 2025
School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, China.
Nowadays, the development of plant extracts as corrosion inhibitors to protect metals from corrosion is a popular research direction. However, given the vast diversity of plant species in nature, it is imperative to explore effective methods to improve screening efficiency in order to quickly identify the corrosion inhibition potential of plants. In this work, a new strategy for developing plant-extracted eco-friendly corrosion inhibitors based on the family and genus of plants is proposed.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!