Endothelial-lined valves assure unidirectional flow in the lymphatic system. In this issue, Saygili Demir et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202207049) demonstrate how continuous repair of these valves occur, beginning with mTOR-activated cell replication in valve sinuses, and followed by cell migration to cover the valve surface.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225616 | PMC |
http://dx.doi.org/10.1083/jcb.202305005 | DOI Listing |
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