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Successful Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus with Celecoxib: A Promising Therapeutic Option.
Am J Case Rep
April 2024
Department of Primary Care and Emergency Medicine, Kyoto University, Kyoto, Japan.
Article Synopsis
- Nephrogenic diabetic insipidus (NDI), especially when linked to lithium ingestion, is challenging to manage clinically, with traditional treatments often yielding minimal improvement.
- *Celecoxib, a selective COX-2 inhibitor, was successfully used to treat a 46-year-old woman with lithium-induced NDI, resulting in significant improvement in her symptoms without adverse effects.
- *This case suggests celecoxib could be a promising alternative treatment for managing lithium-induced NDI, warranting further investigation in clinical settings.
Successful use of trichlormethiazide for diazoxide-related water retention in an infant with trisomy 13.
Pediatr Neonatol
September 2023
Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.
Successful conversion from thiazide to tolvaptan in a patient with stage d heart failure and chronic kidney disease before heart transplantation.
Int Heart J
April 2013
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Chronic kidney disease (CKD) is often complicated with advanced heart failure because of not only renal congestion and decreased renal perfusion but also prolonged use of diuretics at higher doses, which sometimes results in hyponatremia. Preoperative CKD is known to be associated with poor prognosis after heart transplantation (HTx). We experienced a stage D heart failure patient with CKD and hyponatremia who was switched from trichlormethiazide to tolvaptan.
View Article and Find Full Text PDFSuccessful treatment of partial nephrogenic diabetes insipidus with thiazide and desmopressin.
Horm Res
January 2004
Department of Pediatrics, Neonatology and Congenital Disorders, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan.
Objective: To clarify whether combination treatment with desmopressin (DDAVP) and thiazide was clinically effective in a patient with congenital nephrogenic diabetes insipidus (CNDI), we evaluated the treatment in a 7-year-old boy with CNDI who had demonstrated a partial response to DDAVP.
Method: Both volume of urine and the presence of nocturia were determined during treatment.
Result: Neither the usual therapy of a low-salt diet and a thiazide nor intranasal therapy with a large dose of DDAVP was effective.
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