In this work, the phenothiazine fragment with powerful electron-donating ability was specifically selected to construct a multifunctional detector (noted as T1) in double-organelle with near-infrared region I (NIR-I) absorption. The changes of SO/HO content in mitochondria and lipid droplets were observed through red/green channels respectively, which was due to the reaction between benzopyrylium fragment of T1 and SO/HO to achieve red/green fluorescence conversion. Additionally, T1 was endowed with photoacoustic properties deriving from NIR-I absorption to reversibly monitor SO/HOin vivo. This work was significant for more accurately deciphering the physiological and pathological processes in living organisms.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.aca.2023.341181 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!