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| http://dx.doi.org/10.1056/NEJMcpc2201237 | DOI Listing |
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Health and Lifestyle Factors and Dementia Risk Among Former Professional Soccer Players.
JAMA Netw Open
December 2024
School of Psychology & Neuroscience, University of Glasgow, Glasgow, United Kingdom.
Importance: Elite-level contact sport participation is associated with increased dementia risk, which may be attributable to sport-related traumatic brain injury and repetitive head impact exposure. However, the contribution of wider, potentially modifiable dementia risk factors remains uncertain.
Objective: To explore the association of potentially modifiable dementia risk factors with dementia risk among former professional soccer players.
Comprehensive insights into tuberculosis-associated hemophagocytic lymphohistiocytosis: a systematic review.
BMC Infect Dis
November 2024
Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Article Synopsis
- The systematic review investigates Tuberculosis-associated hemophagocytic lymphohistiocytosis (TB-HLH), focusing on its epidemiology, clinical features, and treatment outcomes, highlighting the challenges in diagnosis and management due to the interplay of both conditions.!* -
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Glioblastoma invasion patterns from a clinical perspective-a systematic review.
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Department of Neurosurgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Despite advances in treatment, mechanisms underlying GBM invasion remain incompletely understood. This systematic review synthesizes findings from laboratory and clinical studies to elucidate the molecular mechanisms driving GBM invasion and their implications for prognosis and therapy.
View Article and Find Full Text PDF[Genetic analysis of a child with Congenital insensitivity to pain due to compound heterozygous variants of SCN9A gene].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
November 2024
Department of Medical Genetics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Objective: To explore the genetic etiology of a child featuring multiple fractures and congenital insensitivity to pain (CIP).
Methods: A child who had presented at the West China Hospital of Sichuan University on March 16, 2023 for recurrent fractures and CIP was selected as the study subject. Peripheral blood samples of the child and his parents was collected.
Yellow fever breakthrough infections after yellow fever vaccination: a systematic review and meta-analysis.
Lancet Microbe
December 2024
Amsterdam UMC, Location University of Amsterdam, Center for Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Amsterdam Public Health - Global Health, and Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands. Electronic address:
Article Synopsis
- This systematic review and meta-analysis investigated symptomatic yellow fever breakthrough infections in vaccinated individuals, focusing on cases occurring less than and more than ten years after vaccination.
- The research reviewed 1975 records, ultimately identifying 37 relevant studies that documented 6951 yellow fever cases, with 537 involving vaccinated patients, primarily from Brazil.
- A total of 33 confirmed or probable breakthrough cases were found, with two patients severely ill and resulting in death, highlighting a need for ongoing surveillance in vaccinated populations.
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