We examine the relationship between the top five cryptos and the U.S. S&P500 index from January 2018 to December 2021. We use the novel General-to-specific Vector Autoregression (GETS VAR) and traditional Vector Autoregression (VAR) model to analyze the short- and long-run, cumulative impulse-response, and Granger causality test between S&P500 returns and the returns of Bitcoin, Ethereum, Ripple, Binance and Tether. Additionally, we used the Diebold and Yilmaz (DY) spillover index of variance decomposition to validate our findings. Evidence from the analysis suggests positive short- and long-run effects of historical S&P500 returns on Bitcoin, Ethereum, Ripple, and Tether returns--and negative short- and long-run effects of the historical returns of Bitcoin, Ethereum, Ripple, Binance, and Tether on S&P500 returns. Alternatively, evidence suggests a negative short- and long-run effect of historical S&P500 returns on Binance returns. The cumulative test of impulse-response indicates a shock in historical S&P500 returns stimulates a positive response from cryptocurrency returns while a shock in historical crypto returns triggers a negative response from S&P500 returns. Empirical evidence of bi-directional causality between S&P500 returns and crypto returns suggest the mutual coupling of these market. Although, S&P500 returns have high-intensity spillover effects on crypto returns than crypto returns have on S&P500. This contradicts the fundamental attribute of cryptocurrencies for hedging and diversification of assets to reduce risk exposure. Our findings demonstrate the need to monitor and implement appropriate regulatory policies in the crypto market to mitigate the potential risks of financial contagion.
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http://dx.doi.org/10.1016/j.heliyon.2023.e16179 | DOI Listing |
Eval Rev
January 2025
Global Development Network, Lanzhou University and Director of Evaluation, New Delhi, India.
Official development agencies are increasingly supporting civil society lobby and advocacy (L&A) to address poverty and human rights. However, there are challenges in evaluating L&A. As programme objectives are often to change policies or practices in a single institution like a Government Ministry, L&A programmes are often not amenable to large-n impact evaluation methods.
View Article and Find Full Text PDFExpert Opin Biol Ther
January 2025
OU Stephenson Cancer Center, Oklahoma City.
Introduction: Antibody-drug conjugates (ADCs) are a rapidly evolving class of anti-cancer drugs with a significant impact on management of hematological malignancies including diffuse large B-cell lymphoma (DLBCL). ADCs combine a cytotoxic drug (a.k.
View Article and Find Full Text PDFSleep
January 2025
Department of Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO USA.
Study Objectives: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) may improve sleep dysfunction, a common non-motor symptom of Parkinson disease (PD). Improvement in motor symptoms correlates with DBS-suppressed local field potential (LFP) activity, particularly in the beta frequency (13 - 30 Hz). Although well-characterized in the short term, little is known about the innate progression of these oscillations across the sleep-wake cycle.
View Article and Find Full Text PDFHum Exp Toxicol
January 2025
Department of Gynecology and Obstetrics, Fuyong People's Hospital, Shenzhen, China.
Gestational diabetes mellitus (GDM) is a metabolic disorder that arises during pregnancy and heightens the risk of placental dysplasia. Ginsenoside Re (Re) may stabilize insulin and glucagon to regulate glucose levels, which may improve diabetes-associated diseases. This study aims to investigate the mechanism of Re in high glucose (HG)-induced apoptosis of trophoblasts through endoplasmic reticulum stress (ERS)-related protein CHOP/GADD153.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
January 2025
Discipline of Medical Gerontology, Trinity College Dublin, Ireland.
Background: It has been suggested that dog walking may protect against falls and mobility problems in later life, but little work to date has examined this.The aim of this study was to assess if regular dog walking was associated with reduced likelihood of falls, fear of falling and mobility problems in a large cohort of community-dwelling older people.
Methods: Participants ≥60 years at Wave 5 of The Irish Longitudinal Study on Ageing were included.
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