The majority of young children engage in high levels of screen time. To inform future interventions, knowledge on correlates of screen time is important. This review expands on previous work by focusing on the entire early childhood range, and including a broad focus regarding types of correlates and screens. A literature search (PubMed, Embase, PsycINFO, SPORTDiscus) was performed from 2000 up to October 2021. Included studies (cross-sectional and prospective) examined associations between a potential correlate and screen time (duration or frequency) in typically developing, apparently healthy children aged 0-5 years. Methodological quality was assessed by two independent researchers. Fifty-two of 6,614 studies were included. Two studies had high methodological quality. We found moderate evidence for a positive association between an electronic device in the bedroom, parental screen time, having a TV on at home, descriptive norms and screen time, and a negative association between sleep duration, household features, high value on physical activity, monitoring screen time, being in childcare, parental self-efficacy and screen time. We found no evidence for an association for child sex, body mass index, physical activity, temperament, number of siblings, being a first-born, neighborhood-related factors, socio-economic indicators, and parental marital status, physical activity, weight status, depression, wellbeing, sex, age and positive outcome expectations. The evidence for other investigated correlates was inconsistent or insufficient. Despite the evidence for moderate associations, we were unable to draw strong conclusions. More high-quality research is needed to identify correlates of screen time in early childhood.
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http://dx.doi.org/10.1016/j.pmedr.2023.102214 | DOI Listing |
PLoS One
January 2025
Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India.
Mitogen-activated protein kinase 1 (MAPK1) is a serine/threonine kinase that plays a crucial role in the MAP kinase signaling transduction pathway. This pathway plays a crucial role in various cellular processes, including cell proliferation, differentiation, adhesion, migration, and survival. Besides, many chemotherapeutic drugs targeting the MAPK pathway are used in clinical practice, and novel inhibitors of MAPK1 with improved specificity and efficacy are required.
View Article and Find Full Text PDFGround Water
January 2025
Département de Géologie et de génie géologique, Université Laval, Québec, Canada.
Deep monitoring wells with long screens crossing the transition zone between freshwater and saltwater are often used in coastal areas to characterize fresh groundwater resources and the depth of saline groundwater. However, past studies have demonstrated that long-screen wells can lead to biased observations of the transition zone, since vertical flow within the borehole can modify the shape and elevation of the transition zone in and around the borehole compared to undisturbed conditions without a well. Here, field observations and variable-density numerical flow simulations are used to evaluate, under natural flow conditions, how the installation of long-screen wells can provide time-varying biased observations of the freshwater-saltwater transition zone, and how various aquifer and well parameters affect the magnitude of these biases.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Goldman School of Public Policy, University of California, Berkeley.
Importance: Length of custody is a mechanism by which carceral systems can worsen health. However, there are fewer studies examining US immigration detention, in large part because US immigration detention is largely privately operated and opaque by design.
Objectives: To examine the association between duration spent in US immigration detention with subsequent health outcomes.
Appl Psychol Health Well Being
February 2025
Department of Education and Psychology, Division of Health Psychology, Freie Universität Berlin, Berlin, Germany.
Background: Interventions targeting social media use show mixed results in improving well-being outcomes, particularly for persons with problematic forms of smartphone use. This study assesses the effectiveness of an intervention app in enhancing well-being outcomes and the moderating role of persons' perceptions about problematic smartphone use (PSU).
Methods: In a randomized controlled trial, N = 70 participants, allocated to the intervention (n = 35) or control condition (n = 35), completed weekly online surveys at baseline, post-intervention, and follow-up.
Curr Issues Mol Biol
December 2024
State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 610000, China.
Olfactory receptors (ORs) are members of the transmembrane G protein-coupled receptor superfamily, playing a crucial role in odor recognition, which further mediates crucial biological processes in mammals. In sows, androstenone can trigger sexual behaviors through olfaction, but the underlying mechanism remains to be explored. To efficiently and accurately screen pig olfactory receptors responding to androstenone and the key structure determinant, we adapted the high-throughput RNA-seq strategy to screen the altered genes upon androstenone treatment in the olfactory epithelium of pigs, yielding 1397 downregulated genes.
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