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http://dx.doi.org/10.1177/25158414231173533 | DOI Listing |
Ther Adv Ophthalmol
May 2023
Vitreoretinal Surgery Division, Department of Ophthalmology, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.
J Pharm Biomed Anal
June 2002
Department of Drug Metabolism and Pharmacokinetics, Novartis Institute for Biomedical Research, East Hanover, NJ 07936, USA.
Signal Transduction Inhibitor 571 (STI571, formerly known as CGP 57148B) or Gleevec received fast track approval by the US Food and Drug Administration (FDA) for treatment of chronic myeloid leukemia (CML). STI571 (Gleevec) is a revolutionary and promising new oral therapy for CML, which functions at the molecular level with high specificity. The dramatic improvement in efficacy compared with existing treatments prompted an equally profound increase in the pace of development of Gleevec.
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