AI Article Synopsis
Article Abstract
Background: Cosmeceutical preparations containing growth factors (GFs) are widely used for facial rejuvenation.
Objective: We performed a systematic review to assess the evidence regarding their safety and effectiveness for facial rejuvenation.
Methods: Electronic databases (Cochrane Library, EMBASE, MEDLINE, and Scopus) were searched from 2000 to October 2022 for prospective trials and case series assessing topical GF preparations for facial rejuvenation in 10 or more participants.
Results: Thirty-three studies, including 9 randomized controlled trials (RCTs) and 24 uncontrolled case series, representing 1180 participants receiving 23 different topical preparations containing GFs met the inclusion criteria and were included. Of the 33 studies, nine used a placebo or active control. The GF preparations were applied twice daily in all except two studies, with a mean treatment duration of 3 months. Based on the investigator's assessment, preparations containing GFs induce a modest improvement in skin texture (median < 50%), fine lines/wrinkles (median < 35%), and overall facial appearance (median < 20%) versus baseline. Participant-assessed improvement was generally higher than investigator-assessed response. Three comparative RCTs showed no statistically significant differences between treatments. Studies were limited by heterogeneity with regard to the source and number of GFs used in the preparations, information about additional ingredients, and lack of standardization in the outcome measures. The preparations were associated with a low risk of adverse events. The persistence of the clinical improvements beyond 6 months is not known.
Conclusions: Administration of topical preparations containing GFs appears to be effective for facial skin rejuvenation, as demonstrated by the investigator- and participant-reported outcome measures.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/jocd.15644 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
In Japan, the practice of advance care planning(ACP)for cancer patients may differ from Western countries due to cultural differences and the significant role of family in decision-making. Healthcare providers must consider the physical, psychological, social, and spiritual aspects of care when engaging in ACP, respecting patient autonomy and individual values. Effective communication skills and an understanding of behavioral economics are essential for navigating these discussions, particularly in the home care setting where family caregivers face unique challenges.
View Article and Find Full Text PDFCharacterization of Tip Fold-Over Using Fluoroscopy and Intracochlear Pressure in Cadaver Specimens.
Laryngoscope
December 2024
Department of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado, U.S.A.
Objectives: Cochlear implant array malpositioning is associated with impaired speech perception, vertigo, and facial nerve stimulation. Tip fold-over is a subset of malpositioning that occurs more often with perimodiolar electrodes, but historically it has not been characterized due to lack of knowledge regarding electrode movements of the electrode within the cochlea. The aim of this study was to characterize the mechanics of tip fold-over events and their associated insertion pressure profiles.
View Article and Find Full Text PDFUnveiling the role of sintering temperatures in the physical properties of Cu-Mg ferrite nanoparticles for photocatalytic application.
Heliyon
December 2024
Department of Physics, University of Dhaka, Dhaka, 1000, Bangladesh.
This research presents an explicit analysis of the effects of sintering temperature (T) on the structural, morphological, magnetic, and optical properties of CuMgFeO nanoferrites synthesized via the sol-gel method. To accomplish it, Cu-Mg ferrite NPs were sintered at temperatures ranging from 300 to 800 °C in increments of 100 with a constant holding duration of 5 h. Thermogravimetric analysis was used to observe the degradation of organic components and the thermally stable zone of the material.
View Article and Find Full Text PDFA methodological research for development and psychometric properties of a new Measure to Assess Health Literate Organization (MAHLO-76) in hospital settings.
BMC Health Serv Res
December 2024
Environmental and Occupational Hazards Control Research Center, Research Institute for Health Sciences and Environment, Shahid Beheshti University of Medical Sciences, Tabnak Ave., Daneshjou Blvd., Velenjak, P.O. Box 19835-35511, Tehran, I.R, Iran.
Background: Toward delivering appropriately safe, high quality and effective health care, healthcare organization should be health literate. This paper presents the development and psychometrics of an instrument for assessing the attributes of a health literate hospital which is called MAHLO-76 (Measure to Assess Health Literate Organization) here by authors.
Methods: The current study is methodological research which is involved two phases of tool development and psychometric evaluation.
"No One Really Prepares You": Lived Experiences of Women Division Chiefs in Academic Medicine.
J Womens Health (Larchmt)
December 2024
Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.
Although women have comprised at least 50% of medical school classes for decades, women remain underrepresented in leadership positions. Although the proportion of women division chiefs in the U.S.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!