The literature on childhood tuberculous empyema (TE) is limited. The aim of this study was to examine the clinicopathological characteristics and outcome of paediatric TE and methods of prompt diagnosis and treatment. Between January 2014 and April 2019, 27 consecutive patients with TE aged ≤15 years [mean (SD) 12.2 (3.3), range 6-15] were retrospectively reviewed. The following were reviewed: baseline demographics, symptoms, laboratory and pathological examination, radiographical findings, microbiological data, anti-tuberculous and surgical treatment and clinical outcome. Acid-fast bacillus (AFB) smear, culture, TB real-time (RT) polymerase chain reaction (PCR) and T-SPOT.TB assay were reviewed. Six (60%) of 10 patients were TB-RT-PCR-positive in pus or purulent fluid. Twenty-three of 24 (95.8%) were T-SPOT.TB-positive. Decortication by surgical thoracotomy or thoracoscopy was performed in 22 (81.5%) patients. None of the 27 patients had specific complications such as pyopneumothorax or bronchopleural fistula and all were successfully treated. In childhood TE, aggressive surgical management is associated with a favourable outcome.: AFB, acid-fast bacilli; E, ethambutol; EPTB, extra-pulmonary TB; H, isoniazid; HIC, high-income countries; LMIC, low- and middle-income countries; MTB, ; PCR, polymerase chain reaction; PTB, pulmonary TB; R, rifampicin; RT, real time; TB, tuberculosis; TE, tuberculous empyema; Z, pyrazinamide.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/20469047.2023.2214497 | DOI Listing |
Int J Surg Case Rep
November 2024
Department of General Surgery, Kilimanjaro Christian Medical Center, P.O. Box 3010, Moshi, Tanzania; Kilimanjaro Christian Medical University College, P.O. Box 2240, Moshi, Tanzania.
Gen Thorac Cardiovasc Surg Cases
May 2024
Department of General Thoracic Surgery, Kimitsu Chuo Hospital, 1010 Sakurai, Kisarazu, Chiba, 292-8535, Japan.
Background: Most cases of chronic empyema are caused by acute thoracic empyema or tuberculous pleuritis. Open thoracotomy and decortication are traditional treatments for chronic empyema. However, some cases, such as those with thick calcifications around a large cavity, may be difficult to decorticate in a single surgery.
View Article and Find Full Text PDFInt J Tuberc Lung Dis
November 2024
Division of Thoracic Surgery, Department of Surgery, and, Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.
Cureus
September 2024
Thoracic Surgery, Hull University Teaching Hospital, Hull, GBR.
Empyema is defined as an accumulation of frank pus within the pleural cavity. Empyema necessitans is a rare complication of the pleural space infection when the existing empyema extends into adjacent structures beyond the pleural space, usually into the soft tissue of the chest wall. If severe, it can externalize to the skin.
View Article and Find Full Text PDFCureus
August 2024
Clinic for Anesthesiology and Intensive Therapy, University Clinical Centre of the Republic of Srpska, Banja Luka, BIH.
Diagnosis of tuberculosis (TB) in pregnancy may be challenging. Recommended diagnostic tests often are not sensitive, and additional diagnostic procedures are necessary to confirm disease. Symptoms of TB in pregnancy are often atypical and difficult to diagnose in the early stages of the disease.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!