A new pregnane steroid, jasminanthoside (), together with three known compounds, telosmoside A7 (), syringaresinol (), and methyl 6-deoxy-3--methyl--D-allopyranosyl-(1→4)--D-oleandropyranoside () were isolated from the ethyl acetate extract of roots collected in Vietnam. Their chemical structures were elucidated by NMR and MS spectroscopic data analysis along with the comparison of their data with the published ones in the literature. Although was a known compound, its full NMR data were reported for the first time. All isolated compounds, evaluated for their α-glucosidase inhibition, showed activities stronger than the positive control acarbose. Among them, was the best with the IC value of 7.41 ± 0.59 µM.

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http://dx.doi.org/10.1080/14786419.2023.2216343DOI Listing

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A new pregnane steroid, jasminanthoside (), together with three known compounds, telosmoside A7 (), syringaresinol (), and methyl 6-deoxy-3--methyl--D-allopyranosyl-(1→4)--D-oleandropyranoside () were isolated from the ethyl acetate extract of roots collected in Vietnam. Their chemical structures were elucidated by NMR and MS spectroscopic data analysis along with the comparison of their data with the published ones in the literature. Although was a known compound, its full NMR data were reported for the first time.

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