Simultaneous ground-state cooling of multiple degenerate mechanical modes is a difficult issue in optomechanical systems, owing to the existence of the dark mode effect. Here we propose a universal and scalable method to break the dark mode effect of two degenerate mechanical modes by introducing cross-Kerr (CK) nonlinearity. At most, four stable steady states can be achieved in our scheme in the presence of the CK effect, unlike the bistable behavior of the standard optomechanical system. Under a constant input laser power, the effective detuning and mechanical resonant frequency can be modulated by the CK nonlinearity, resulting in an optimal CK coupling strength for cooling. Similarly, there will be an optimal input laser power for cooling when the CK coupling strength stays fixed. Our scheme can be extended to break the dark mode effect of multiple degenerate mechanical modes by introducing more than one CK effect. To fulfill the requirement of the simultaneous ground-state cooling of N multiple degenerate mechanical modes, N - 1 CK effects with different strengths are needed. Our proposal provides new, to the best of our knowledge. insights into dark mode control and might pave the way to manipulating multiple quantum states in a macroscopic system.
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http://dx.doi.org/10.1364/OL.473885 | DOI Listing |
Bioact Mater
April 2025
Department of Regenerative Medicine, College of Medicine, Soonchunhyang University, Cheonan, Republic of Korea.
Articular cartilage has a limited self-healing capacity, leading to joint degeneration and osteoarthritis over time. Therefore, bioactive scaffolds are gaining attention as a promising approach to regenerating and repairing damaged articular cartilage through tissue engineering. In this study, we reported on a novel 3D bio-printed proteinaceous bioactive scaffolds combined with natural porcine cancellous bone dECM, tempo-oxidized cellulose nanofiber (TOCN), and alginate carriers for TGF-β1, FGF-18, and ADSCs to repair cartilage defects.
View Article and Find Full Text PDFJ Biomed Mater Res B Appl Biomater
February 2025
Tianjin Hospital, Tianjin, China.
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View Article and Find Full Text PDFAnn Med
December 2025
Department of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, The People's Republic of China.
Objectives: The incidence rate of intervertebral disc degeneration (IVDD) is increasing year by year, which brings great harm to our health. The change of biomechanical factors is an important reason for IVDD. Therefore, more and more studies use finite element (FE) models to analyze the biomechanics of spine.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Université de Lorraine, CNRS, Institut Jean Lamour, Nancy, 54000, France.
ℤ-classified higher-order topological insulators (HOTIs) with chiral-symmetric higher-order topological phases protected by multipole chiral numbers (MCNs) have attracted extensive interest recently. However, how to design artificial ℤ-classified HOTIs with multiple topological phases remains an unresolved issue. Here, multiorbital degrees of freedom are introduced to acoustic crystals and the various methods of topological phase transitions are achieved for the orbital ℤ-classified HOTIs.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Shanxi Key Laboratory of Biomedical Metal Materials, College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
The interaction between biomaterials and immune system is a critical area of research, especially in tissue engineering and regenerative medicine. A fascinating and less explored aspect involves the immunomodulatory behaviors of macrophage (MΦ)-derived exosomes induced by biomaterial surfaces. Herein, untreated surface, nanostructured surface, and type I collagen (Col-I)-decorated nanostructured surface of titanium implants are chosen to culture MΦs, followed by extraction of MΦ-derived exosomes and investigation of their immunomodulatory functions and mechanisms.
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