Apart from squat jumps, countermovement jumps (CMJ), and drop jumps, differences among other jump variations are not as well researched, making data-driven exercise selection difficult. To address this gap, this study compared selected concentric and eccentric jump parameters of maximal effort CMJ, hurdle jumps over 50 cm hurdle (HJ), and box jumps onto a 50 cm box (BJ). Twenty recreationally trained men (25.2 ± 3.5 years) performed 3 repetitions of CMJs, HJs, and BJs, each on separate days. The data were collected using force platforms and a linear position transducer. The mean of 3 trials of each jump variation was analyzed using repeated measures ANOVA and Cohen's d. Countermovement depth was significantly greater ( ≤ 0.05) and peak horizontal force significantly lower during CMJ compared to HJ and BJ. However, there were no differences in peak velocity, peak vertical and resultant force, and total impulsion time. Finally, BJ significantly decreased peak impact force by ~51% compared to CMJ and HJ. Therefore, the propulsive parameters of HJ and BJ seem to be similar to CMJ, despite CMJ having a greater countermovement depth. Furthermore, overall training load can be decreased dramatically by using BJ, which reduced peak impact force by approximately half.
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http://dx.doi.org/10.3390/jfmk8020061 | DOI Listing |
Biomedicines
November 2024
Bio and Emerging Technology Institute (BETin), Addis Ababa P.O. Box 5954, Ethiopia.
The field of personalized medicine is undergoing a transformative shift through the integration of multi-omics data, which mainly encompasses genomics, transcriptomics, proteomics, and metabolomics. This synergy allows for a comprehensive understanding of individual health by analyzing genetic, molecular, and biochemical profiles. The generation and integration of multi-omics data enable more precise and tailored therapeutic strategies, improving the efficacy of treatments and reducing adverse effects.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Translational Oncology Research Center (TORC), Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation (QF), Doha P.O. Box 34110, Qatar.
Background: Chemoresistance in triple-negative breast cancer (TNBC) presents a significant clinical hurdle, limiting the efficacy of treatments like doxorubicin. This study aimed to explore the molecular changes associated with doxorubicin resistance and identify potential therapeutic targets to overcome this resistance, thereby improving treatment outcomes for TNBC patients.
Methods: Doxorubicin-resistant (DoxR) TNBC models (MDA-MB-231 and BT-549) were generated by exposing cells to increasing concentrations of doxorubicin.
Curr Res Food Sci
November 2024
Food Process Engineering Group, Wageningen University and Research, P.O. Box 17, 6700, AA Wageningen, the Netherlands.
Insect-based food ingredients are emerging as sustainable protein sources, but their production requires ensuring microbial safety and inactivation of endogenous enzymes to avoid undesirable proteolysis, without compromising protein structure. While traditional thermal processing affects the protein structure, the potential of pulsed electric field (PEF) technology to inactivate microorganisms in lesser mealworm and house cricket slurries at pH 3 while simultaneously retaining the native protein structure is yet unexplored. Lesser mealworm and house cricket slurries at pH 3 were subjected to continuous and batch PEF treatments with varying intensities (0-450 kJ/kg).
View Article and Find Full Text PDFMicrobiol Spectr
December 2024
Statistics Department, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Unlabelled: Mediation analysis has emerged as a versatile tool for answering mechanistic questions in microbiome research because it provides a statistical framework for attributing treatment effects to alternative causal pathways. Using a series of linked regressions, this analysis quantifies how complementary data relate to one another and respond to treatments. Despite these advances, existing software's rigid assumptions often result in users viewing mediation analysis as a black box.
View Article and Find Full Text PDFHealthcare (Basel)
December 2024
Fondazione per la Ricerca Farmacologica Gianni Benzi Onlus, 70124 Bari, Italy.
EPIICAL (Early treated Perinatally HIV-Infected individuals: Improving Children's Actual Life) is a consortium of European and non-European research-driven organizations inter-connected with the aim of establishing a clinical and experimental platform for the early identification of novel therapeutic strategies for the pediatric Human Immunodeficiency Virus (HIV). Within the EPIICAL project, several pediatric clinical studies were conducted, requiring the collection and transfer of biological samples and associated data across boundaries within and outside Europe. To ensure compliance with the applicable rules on pediatric data and sample transfer and to support the efforts of academic partners, which may not always have the necessary expertise and resources in place for designing, managing and conducting multi-national studies, the consortium established a dedicated expert Working Group.
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