AI Article Synopsis
- Antimetropia is a unique form of anisometropia where one eye is nearsighted (myopic) and the other is farsighted (hyperopic), allowing researchers to study the emmetropisation process in the same individual while controlling for genetics and environment.
- The study focused on 29 antimetropic subjects older than six years, comparing various ocular measurements like axial length and retinal thickness between the myopic and hyperopic eyes.
- The results showed significant differences in ocular parameters between the eyes, with myopic eyes displaying certain structural variations, and amblyopia occurring in some subjects, though not significantly different between myopic and hyperopic groups.
Article Abstract
Clinical Relevance: Antimetropia is a rare type of anisometropia in which one eye is myopic and the fellow is hyperopic, This optical condition condition permits the evaluation of both sides of the emmetropisation process failure in the same individual by minimising genetic and environmental factors.
Background: This study aimed to evaluate the ocular biometric, retinal, and choroidal characteristics of myopic and hyperopic eyes of antimetropic subjects older than six years.
Methods: In this retrospective study, myopic and hyperopic eyes of 29 antimetropic patients with a spherical equivalent (SE) difference of at least 2.00D between the eyes were included. Axial length (AL), mean corneal keratometry, anterior chamber depth, the proportion of anterior chamber depth in AL, crystalline lens power, central macular thicknesses, disc-to-fovea distance, fovea-disc angle, peripapillary retinal nerve fibre layer (RNFL) thicknesses, and subfoveal choroidal features were compared between the eyes. The prevalence of amblyopia was determined. Refractive parameters and total astigmatic profile were evaluated in eyes with and without amblyopia.
Results: The median absolute SE and AL differences between the eyes were 3.50D (interquartile range:1.75) and 1.18 mm (interquartile range:0.76), respectively ( < 0.001). Myopic eyes had lower crystalline lens power and proportion of anterior chamber depth in AL, and longer disc-to-fovea distance. Macular thicknesses, global RNFL, and temporal RNFL were thicker in myopic eyes, and there was no difference in other RNFL quadrants. Despite the increase in the choroidal vascularity index, other choroidal parameters were decreased in myopic eyes. Amblyopia was found in three of the myopic eyes and seven of the hyperopic eyes ( = 0.343). The highest interocular SE and AL difference and the highest frequency of anisoastigmatism were observed in patients with amblyopia in the myopic eye.
Conclusion: Each ocular structure may respond differently to, or may be affected differently by, ametropic conditions.
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| http://dx.doi.org/10.1080/08164622.2023.2213825 | DOI Listing |
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