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http://dx.doi.org/10.3389/fendo.2023.1202275 | DOI Listing |
Antioxidants (Basel)
January 2025
Istituto di Analisi dei Sistemi ed Informatica "Antonio Ruberti", National Research Council, 00185 Rome, Italy.
Reactive oxygen and nitrogen species (ROS; RNS) are natural bioproducts of cellular metabolism, particularly produced within the mitochondria during energy production [...
View Article and Find Full Text PDFAntioxidants (Basel)
January 2025
Guangdong Provincial Key Laboratory IRADS, Department of Life Sciences, BNU-HKBU United International College, Zhuhai 519087, China.
Oxidative stress is caused by various intrinsic and extrinsic factors [...
View Article and Find Full Text PDFCurr Issues Mol Biol
December 2024
Agriculture and Life Science Research Institute, Kangwon National University, Chuncheon 24341, Republic of Korea.
Despite significant advancements in plant breeding research, the challenges posed by a growing global population, the impact of abiotic and biotic stresses, and the uncertainties of climate change necessitate continued focus and innovation in plant breeding and genetic studies [...
View Article and Find Full Text PDFFront Cell Dev Biol
January 2025
Department of Cell and Cancer Biology, College of Medicine and Life Sciences, The University of Toledo, Toledo, OH, United States.
Heat Shock Factor 1 (HSF1) is a major transcriptional factor regulating the heat shock response and has become a potential target for overcoming cancer chemoresistance. This review comprehensively examines HSF1's role in chemoresistance and its potential as a therapeutic target in cancer. We explore the complex, intricate mechanism that regulates the activation of HSF1, HSF1's function in promoting resistance to chemotherapy, and the strategies used to manipulate HSF1 for therapeutic benefit.
View Article and Find Full Text PDFFront Vet Sci
January 2025
Clinic of Reproductive Medicine, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Brachycephalic breeds suffer from respiratory distress known as brachycephalic obstructive airway syndrome (BOAS) and the multiple comorbidities associated with it. Targeted breeding toward a more BOAS-free phenotype requires accurate and least invasive detection of BOAS severity grades that are accessible and accepted by the breeders and kennel clubs. This study aimed to compare the-outcome of morphometric anatomical examination with functional tests such as exercise tests and plethysmography for the detection of BOAS severity in a group of 84 French Bulldogs.
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