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Multisystemic Sarcoidosis in the Primary Care Setting: A Case Report.
Cureus
December 2024
Family Medicine, Unidade de Saúde Familiar (USF) Amato Lusitano, Unidade Local de Saúde (ULS) de Amadora/Sintra, Amadora, PRT.
Sarcoidosis is a rare, multisystemic disease of unknown etiology, characterized by noncaseating granulomas in various organs. The disease often presents with nonspecific symptoms that complicate the diagnosis. We describe the case of a 31-year-old woman who presented to her family doctor with weight loss, cervical lymphadenopathy, parotid edema, and cutaneous lesions, initially raising suspicion of a lymphoproliferative disorder.
View Article and Find Full Text PDFSevere headache as the first presentation of post-COVID-19 brain and spinal cord injury resembling neurosarcoidosis.
Postep Psychiatr Neurol
September 2024
Department of Medical Virology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Purpose: Sarcoidosis, a multi-organ granulomatous disease, occasionally involves the nervous system, presenting as neurosarcoidosis. The following case demonstrates a potential association between COVID-19 and brain and spinal cord injury mimicking neurosarcoidosis.
Case Description: A 51-year-old woman presented with persistent holocranial headache, nausea, vertigo, and neurological deficits one month after a COVID-19 hospitalization.
Trends in All-Cause Mortality Among US Veterans With Sarcoidosis, 2004-2022.
Chest
November 2024
San Francisco Veterans Affairs Healthcare System, University of California, San Francisco, San Francisco, CA; Department of Medicine, University of California, San Francisco, San Francisco, CA.
Article Synopsis
- Sarcoidosis is a complex disease with various outcomes, and this study aims to explore the trends in mortality among U.S. Veterans diagnosed with the condition from 2004 to 2022, focusing on demographics and geographic differences.
- The research used electronic health records to analyze data from 23,745 Veterans, finding that all-cause mortality increased by 4.7% annually and was significantly higher in Black Veterans compared to White Veterans.
- Factors such as older age, male sex, Black race, and living in the Northeast increased mortality risk, while socioeconomic status did not significantly change mortality trends in the subgroup analysis.
Histopathological Evaluation of Somatostatin Receptor 2 Expression in Myocarditis-Rationale for the Diagnostic Use of Somatostatin Receptor Imaging.
Diagnostics (Basel)
October 2024
Department of Clinical Pathology, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.
Background/objectives: Myocarditis is an inflammatory disease of the myocardium and remains to this day a challenging diagnosis. A promising novel imaging method uses the expression of somatostatin receptors (SSTRs) on inflammatory cells to visualize myocardial inflammation. However, little is known about the histopathological correlate of SSTR imaging in different forms of myocarditis.
View Article and Find Full Text PDFMultisystem diseases in the abdomen and pelvis: imaging manifestations and diagnostic roles of cross-sectional imaging.
Abdom Radiol (NY)
October 2024
Department of Radiology, Konkuk University Medical Center, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Republic of Korea.
Systemic diseases, such as IgG4-related disease, sarcoidosis, and amyloidosis, usually involve multiple systems or organs simultaneously or sequentially. The gastrointestinal tract, hepatobiliary system, and genitourinary tract are commonly involved in many multisystem diseases and can also be the first sites with disease involvement. Cross-sectional imaging, such as CT and MR, plays an important role in the diagnosis and management of multisystem diseases by aiding in the evaluation of multiorgan involvement.
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