AI Article Synopsis
- There have been big improvements in understanding and studying neuropathic pain over the last few decades.
- Better tools, like questionnaires, help doctors figure out when people have this kind of pain, including new types related to COVID-19.
- Finding the best treatments is still tough, and new methods, like combining different medicines and using techniques that don't involve drugs, are being explored for better care.
Article Abstract
Over the past few decades, substantial advances have been made in neuropathic pain clinical research. An updated definition and classification have been agreed. Validated questionnaires have improved the detection and assessment of acute and chronic neuropathic pain; and newer neuropathic pain syndromes associated with COVID-19 have been described. The management of neuropathic pain has moved from empirical to evidence-based medicine. However, appropriately targeting current medications and the successful clinical development of drugs acting on new targets remain challenging. Innovative approaches to improving therapeutic strategies are required. These mainly encompass rational combination therapy, drug repurposing, non-pharmacological approaches (such as neurostimulation techniques), and personalised therapeutic management. This narrative review reports historical and current perspectives regarding the definitions, classification, assessment, and management of neuropathic pain and explores potential avenues for future research.
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| http://dx.doi.org/10.1016/j.bja.2023.04.021 | DOI Listing |
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