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Streptococcal Toxic Shock Syndrome (STSS) Secondary to Monoarticular Septic Arthritis Leading to Multiorgan Failure in a Patient without Underlying Comorbidities: Emphasizing Early Diagnosis and Management Strategies.
Infect Disord Drug Targets
January 2025
HCA Healthcare Las Palmas/Del Sol Internal Medicine Program.
Background: Streptococcal Toxic Shock Syndrome (STSS) is a life-threatening condition caused by bacterial toxins. The STSS triad encompasses high fever, hypotensive shock, and a "sunburn-like" rash with desquamation. STSS, like Toxic Shock Syndrome (TSS), is a rare complication of streptococcal infec-tions caused by Group A Streptococcus (GAS), Streptococcal pyogenes (S.
View Article and Find Full Text PDFSMARCB1/INI-1-Deficient sinonasal carcinoma demonstrates a poor prognosis but favorable clinical outcomes after PD-1/PD-L1 inhibitor therapy: A case series.
Sci Prog
January 2025
Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Despite advances in multimodal cancer therapy, such as combining radical surgery with high-intensity chemoradiotherapy, for SMARCB1/INI-1-deficient sinonasal carcinoma (SDSC), the prognosis of patients remains poor. Immunotherapy is gaining increasing popularity as a novel treatment strategy for patients with SMARCB1/INI-1-deficient tumors. Herein, we report on the management of three patients with SDSC who received PD-1/PD-L1 inhibitor therapy as a part of multimodal therapy based on surgery and chemoradiotherapy.
View Article and Find Full Text PDFWe present a case of a patient who sustained a distal radius fracture and underwent volar plate fixation. Despite initial non-operative management, subsequent corrective osteotomy was required due to malunion. Eighteen months later, the patient presented with an inability to extend the thumb, leading to a diagnosis of extensor pollicis longus (EPL) tendon rupture.
View Article and Find Full Text PDFA Narrative Review of the Impact of Sleep on Athletes: Sleep Restriction Causes and Consequences, Monitoring, and Interventions.
Cureus
December 2024
Physical Medicine and Rehabilitation, Unidade de Saúde Local de Lisboa Ocidental, Lisboa, PRT.
This narrative review synthesizes evidence on the impact of sleep on athletic performance, the prevalence and causes of sleep disturbances, and effective monitoring and intervention strategies to enhance sleep quality and duration. A comprehensive review of case studies, observational studies, randomized controlled trials, systematic reviews, and meta-analyses was conducted using PubMed, Cochrane Library, and Google Scholar up to July 2024. Sleep plays a crucial role in the overall well-being and performance of athletes, yet sleep issues are highly prevalent due to factors such as competition schedules, psychological stress, and travel across time zones.
View Article and Find Full Text PDFSuccessful Management of COVID-19-Associated Systemic Capillary Leak Syndrome Using Veno-Venous Extracorporeal Membrane Oxygenation: A Case Report.
Cureus
December 2024
Department of Critical Care Medicine, St. Luke's International Hospital, Tokyo, JPN.
Systemic capillary leak syndrome (SCLS) is a rare and life-threatening disorder characterized by acute hypotension, hypoalbuminemia, and hemoconcentration, which often results in severe respiratory complications, such as pulmonary edema. SCLS can be triggered by infections, including COVID-19, and is associated with a high mortality rate. Here, we report a case of COVID-19-associated SCLS in a 68-year-old man.
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