AI Article Synopsis
- * He was treated for respiratory failure and acute kidney injury (AKI), requiring temporary use of a mechanical ventilator and hemodialysis.
- * A biopsy indicated he suffered from myoglobin cast nephropathy, and while 14 other transplant patients contracted SARS-CoV-2, only this man developed AKI.
Article Abstract
When COVID-19 affects patients with risk factors such as chronic kidney disease or on immunosuppressive drugs, they often rapidly become seriously ill. We describe a 50-year-old man who was affected with SARS-CoV-2 and had undergone an ABO-compatible living-donor kidney transplantation from his father 14 years ago because of end-stage renal failure due to hypertensive nephrosclerosis. He had continued on immunosuppressive drugs and completed vaccination twice (9 months ago and 6 months ago) with messenger RNA (mRNA) vaccines against SARS-CoV-2. However, he was temporarily on a mechanical ventilator due to respiratory failure and hemodialysis due to acute kidney injury (AKI). He was finally weaned from the ventilator and hemodialysis by taking steroid and antiviral drugs. Echo-guided renal biopsy revealed myoglobin cast nephropathy. We experienced 14 outpatients after living-donor kidney transplantation infected with SARS-CoV-2, but only this case developed AKI.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076507 | PMC |
| http://dx.doi.org/10.1016/j.transproceed.2023.03.068 | DOI Listing |
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