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A Retrospective Comparison of Aeroallergen Sensitization Among Different Allergic Diseases in Guangzhou, China.
Mediators Inflamm
January 2025
Department of Otolaryngology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.
Numerous studies have reported on the types of aeroallergen sensitization in various pediatric allergic diseases, but limited data compared the types of aeroallergen sensitization across different pediatric allergic diseases. The aim of this study is to explore the nature and significance of aeroallergen sensitization in diverse pediatric allergic conditions. A comparative analysis was carried out on aeroallergen sensitization in children suffering from allergic diseases who visited the Otolaryngology, Respiratory, and Dermatology Departments between January 2019 and December 2023.
View Article and Find Full Text PDFTapinarof Improved Outcomes and Sleep for Patients and Families in Two Phase 3 Atopic Dermatitis Trials in Adults and Children.
Dermatol Ther (Heidelb)
January 2025
Dermavant Sciences, Inc., Morrisville, NC, USA.
Introduction: Tapinarof is a topical aryl hydrocarbon receptor (AhR) agonist in development for the treatment of atopic dermatitis (AD). In two phase 3 trials (ADORING 1 and 2), tapinarof cream 1% once daily (QD) demonstrated significant efficacy and was well tolerated in patients down to age 2 years with AD. Here, we evaluate patient-reported outcomes (PROs), including family impact, with tapinarof in ADORING 1 and 2.
View Article and Find Full Text PDFInvestigating the impact of perceived social stigmatization and social appearance anxiety on quality of life among patients with facial skin diseases.
Arch Dermatol Res
January 2025
National Institute of Psychology, Quaid-i-Azam University, Islamabad, Pakistan.
Background: This study investigates the interplay between perceived social stigmatization, social appearance anxiety, and quality of life in individuals with facial skin diseases. Furthermore, it undertakes the psychological and social impact of visible skin diseases, such as acne, atopic dermatitis, rosacea, enlarged pores, and vitiligo, on individuals' quality of life. These conditions not only cause physical discomfort but also lead to feelings of sadness, anxiety, and low self-esteem.
View Article and Find Full Text PDFSoothing the Itch: The Role of Medicinal Plants in Alleviating Pruritus in Palliative Care.
Plants (Basel)
December 2024
Academic Clinical Center of Trás-os-Montes and Alto Douro (CACTMAD), University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.
Chronic pruritus, or persistent itching, is a debilitating condition that severely impacts quality of life, especially in palliative care settings. Traditional treatments often fail to provide adequate relief or are associated with significant side effects, prompting interest in alternative therapies. This review investigates the antipruritic potential of eight medicinal plants: chamomile (), aloe vera (), calendula (), curcumin (), lavender (), licorice (), peppermint (), and evening primrose ().
View Article and Find Full Text PDFThree versions of an atopic dermatitis case report written by humans, artificial intelligence, or both: Identification of authorship and preferences.
J Allergy Clin Immunol Glob
February 2025
Big Data Department, Faculdade Israelita de Ciências da Saúde Albert Einstein, São Paulo, Brazil.
Background: The use of artificial intelligence (AI) in scientific writing is rapidly increasing, raising concerns about authorship identification, content quality, and writing efficiency.
Objectives: This study investigates the real-world impact of ChatGPT, a large language model, on those aspects in a simulated publication scenario.
Methods: Forty-eight individuals representing 3 medical expertise levels (medical students, residents, and experts in allergy or dermatology) evaluated 3 blinded versions of an atopic dermatitis case report: one each human written (HUM), AI generated (AI), and combined written (COM).
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