Human breath is an easily, noninvasively obtained substance. It offers insight into metabolism and is used to diagnose disaccharide malabsorption, infection, small bowel bacterial over growth, and transit times. Herein, we discuss the readily available clinical breath tests, how they function, how they are administered and interpreted and some pitfalls in their use.
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http://dx.doi.org/10.1097/PG9.0000000000000027 | DOI Listing |
Eur J Prev Cardiol
March 2025
Clinical Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Via Morandi 30, Milan 20097, Italy.
For most patients with chronic, progressive illnesses, maintaining good quality of life (QoL), with preserved functional capacity, is just as crucial as prolonging survival. Patients with heart failure (HF) experience much worse QoL and effort intolerance than both the general population and people with other chronic conditions, since they present a range of physical and psychological symptoms, including shortness of breath, chest discomfort, fatigue, fluid congestion, trouble with sleeping, and depression. These symptoms reduce patients' capacity for daily social and physical activity.
View Article and Find Full Text PDFEur J Heart Fail
March 2025
Clinical Cardiology, IRCCS Policlinico San Donato, Milan, Italy.
For most patients with chronic, progressive illnesses, maintaining good quality of life (QoL), with preserved functional capacity, is just as crucial as prolonging survival. Patients with heart failure (HF) experience much worse QoL and effort intolerance than both the general population and people with other chronic conditions, since they present a range of physical and psychological symptoms, including shortness of breath, chest discomfort, fatigue, fluid congestion, trouble with sleeping, and depression. These symptoms reduce patients' capacity for daily social and physical activity.
View Article and Find Full Text PDFPathog Immun
March 2025
MRC Clinical Trials Unit, University College London, London, United Kingdom.
Background: In the field of tuberculosis and non-tuberculous mycobacterial (NTM) disease we are looking back on an exciting year 2024 with more than 10,000 publications listed in PubMed.
Methods: Our aim, to review the scientific literature of the year 2024, is challenged by the enormous number of publications. Therefore, if your article is not included or your favorite field of mycobacteriology not covered, please forgive us.
Indian J Otolaryngol Head Neck Surg
January 2025
Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Warsaw, 1a Banacha Str., Warsaw, 02-097 Poland.
Upper airway stenosis is a potentially life-threatening condition that can occur at the level of the larynx, trachea, or multiple sites. It compromises breathing, coughing up secretions or voice production. To date, a wide range of endoscopic and open procedures have been described.
View Article and Find Full Text PDFBiosens Bioelectron
December 2024
Centre for Advanced Materials and Industrial Chemistry (CAMIC), School of Science, RMIT University, GPO Box 2476, Melbourne, Victoria, 3001, Australia; School of Engineering, RMIT University, Melbourne, Victoria, 3001, Australia. Electronic address:
Human breath has been recognized as a complex yet predictive mixture of volatile organic compounds (VOCs) and inorganic gas species that can be utilized to non-invasively diagnose common diseases. Current laboratory techniques such as gas chromatography/mass spectrometry (GC/MS) and high-performance liquid chromatography (HPLC), are capable of VOC detection down to ppm concentrations. However, these methods are expensive, non-portable, require pre-processing of the exhaled VOCs, and expert operators, making them unsuitable for wide-spread use.
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