It was isolated and identified MR-Le virus from Wistar rats with myelogenous leukemia. The comparison of isolated in vivo and in vitro MR-Le virus with endogenous oncovirus RaLV in protein profile as well as results of molecular hybridization pointed out that RaLV did not participate in the induction of MR leukemia. The question about the role of MR-Le virus in the etiology of MR leukemia is opened now.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Variation in Employment in Healthcare Occupations and County-Level Differences in COVID-19 Cases in the United States of America.
J Occup Environ Med
July 2021
Premedical and Health Studies Program, School of Arts and Sciences, MCPHS University, Boston, Massachusetts, USA (Mr Le); Public Health Program, School of Arts and Sciences, MCPHS University, Boston, Massachusetts (Mr Hawkins).
Objective: To study how county-level differences in employment in healthcare occupations contributes to county-level differences in COVID-19 cases.
Method: The number of active COVID-19 cases were gathered from the Johns Hopkins University Coronavirus Resource Center weekly between April 22, 2020 and July 1, 2020. Data for the number of workers employed in healthcare occupations were collected at the county-level from the American Community Survey.
It was isolated and identified MR-Le virus from Wistar rats with myelogenous leukemia. The comparison of isolated in vivo and in vitro MR-Le virus with endogenous oncovirus RaLV in protein profile as well as results of molecular hybridization pointed out that RaLV did not participate in the induction of MR leukemia. The question about the role of MR-Le virus in the etiology of MR leukemia is opened now.
View Article and Find Full Text PDFThe rat MR-leukemia (MR-Le) induced in Wistar rats by methylcholanthrene and whole-body irradiation, has been shown to be transmitted by means of cell-free filtrates of spleen and liver extracts. These earlier results lead us to determine the expression of retroviral functions by MR-Le myeloblasts in vivo and in vitro. DNA polymerase activity associated with particulate material purified from plasma of rats carrying MR-Le and from MR-Le tissue culture fluid, increased with the number of MR-Le myeloblasts.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!