Aim: The purpose of this study was to evaluate the efficacy of 3% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), and chitosan nanoparticles against using the agar disc-diffusion test.
Materials And Methods: Strain of was cultivated in Sabouraud Dextrose Agar. Chitosan nanoparticles were synthesized using an ionic gelation method. Four groups were made according to the irrigants used. Group 1: 3% NaOCl, Group 2: 2% CHX, Group 3: chitosan nanoparticles, and Group 4: saline as control. Discs were added with the different irrigants and placed in a dish containing . The plates were incubated at 37°C for 24h. The zone of inhibition was measured in millimeter.
Results: Statistical analysis was performed using the test of one-way variance (ANOVA) and Tukey. Group 1 showed significantly higher zone of inhibition compared to Groups 2 and 3 ( < 0.05). There were no significant differences between the zones of inhibition of Groups 2 and 3 ( < 0.05).
Conclusion: Chitosan nanoparticles and 2% CHX have similar efficacy against , whereas 3% NaOCl was significantly better than both chitosan nanoparticles and CHX.
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| http://dx.doi.org/10.4103/jcd.jcd_617_22 | DOI Listing |
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