A method for C(sp)-C(sp) cross-coupling of amines is described. Primary amines are converted to 1,2-dialkyldiazenes by treatment with -nosylhydroxylamines in the presence of atmospheric oxygen. Denitrogenation of the diazenes with an iridium photocatalyst then forges the C-C bond. The substrate scope accommodates a broad latitude of functionality, including heteroaromatics and unprotected alcohols and acids.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405275 | PMC |
| http://dx.doi.org/10.1021/jacs.3c03634 | DOI Listing |
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