Background: Neoplasia of ectopic thyroid components is relatively rare in thyroglossal duct cysts. We report a case of histopathologically confirmed papillary thyroid carcinoma in a thyroglossal duct cyst, discuss its clinical characteristics of, and provide reference for diagnosis and treatment.
Case Description: We presented a 25-year-old female went to hospital because of "a tumor in her neck". She was preoperatively diagnosed with thyroglossal duct cyst by cervical ultrasound, and enhanced computed tomography (CT). However, the solid component of the mass suggested intracystic neoplasia. She underwent Sistrunk surgical resection, and postoperative histopathology showed thyroglossal duct cyst, and papillary thyroid carcinoma in the cyst wall. The patient had no high-risk factors and had a low risk of recurrence. After full disclosure, the patient chose close follow-up, and to date there has been no recurrence.
Conclusions: There are controversies regarding the origin of thyroglossal duct cyst carcinoma and the extent of surgery required, and a lack of unified treatment guidelines. We recommend tailoring individualized treatment based on individual risk stratification. By reporting this case, we hope to inform surgeons of the various abnormalities that may occur in ectopic thyroid tissue.
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http://dx.doi.org/10.21037/gs-23-102 | DOI Listing |
Cureus
November 2024
General Surgery, Gujarat Cancer Society (GCS) Medical College Hospital and Research Centre, Ahmedabad, IND.
Thyroglossal duct cysts (TGDCs) are typically located in the midline of the neck. Carcinomas arising within these cysts are extremely rare, with papillary carcinoma being the most common type. Diagnosis is generally confirmed postoperatively following excision.
View Article and Find Full Text PDFEur Ann Otorhinolaryngol Head Neck Dis
December 2024
Service ORL-CCF, CHU de Grenoble-Alpes (CHUGA), Grenoble, France; Secteur santé, université Grenoble-Alpes (UGA), Grenoble, France.
Research and knowledge in human embryology greatly progressed during the second half of the 19th century. This allowed optimization of surgical treatment of branchial deformities and cervical cysts in the light of their embryological development. In 1920, Walter Ellis Sistrunk described an embryologically-based technique for resection of thyroglossal duct fistulae and cysts.
View Article and Find Full Text PDFCureus
October 2024
Otolaryngology - Head and Neck Surgery, St. Luke's University Health Network, Bethlehem, USA.
Sistrunk procedure is the treatment for thyroglossal duct cysts (TGDC), the majority of which occur in children. TGDC are very rare in the elderly and account for under 2% of cases. Management in this population, where risks of surgery may outweigh benefits, is unclear.
View Article and Find Full Text PDFUltrasound
April 2024
Department of ENT, Head and Neck Surgery and Plastic Surgery, Klinikum Bad Salzungen, Bad Salzungen, Germany.
Gland Surg
October 2024
Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Background: Ectopic thyroid carcinoma in the mandible is extraordinarily rare; few histologically proven cases have been reported in the literature. Embryologically, cases of ectopic thyroid occur with a developmental abnormality during the migration of the thyroid gland from the floor of the primitive foregut to its final position in the neck. Ectopic thyroid tissue can be found around the course of the thyroglossal duct or laterally in the neck, and even in the mediastinum or below the diaphragm.
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