Hydrogels have emerged as promising materials for flexible electronics due to their unique properties, such as high water content, softness, and biocompatibility. In this perspective, we provide an overview of the development of hydrogels for flexible electronics, with a focus on three key aspects: mechanical properties, interfacial adhesion, and conductivity. We discuss the principles of designing high-performance hydrogels and present representative examples of their potential applications in the field of flexible electronics for healthcare. Despite significant progress, several challenges remain, including improving the antifatigue capability, enhancing interfacial adhesion, and balancing water content in wet environments. Additionally, we highlight the importance of considering the hydrogel-cell interactions and the dynamic properties of hydrogels in future research. Looking ahead, the future of hydrogels in flexible electronics is promising, with exciting opportunities on the horizon, but continued investment in research and development is necessary to overcome the remaining challenges.
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http://dx.doi.org/10.1021/acsnano.3c02897 | DOI Listing |
Trends Microbiol
March 2025
Singapore Centre for Environmental Life Sciences Engineering, National University of Singapore, Singapore 117456, Singapore; Department of Biological Sciences, National University of Singapore, Singapore 117558, Singapore; NUS Environmental Research Institute, National University of Singapore, Singapore 117411, Singapore. Electronic address:
Owing to its biochemical flexibility, sulfur (S) is uniquely poised to fulfill versatile roles in plant-microbe interactions - impacting their metabolism with significant consequences for plant health and the global S cycle. We present evidence that the diversity of S-metabolic genes in plant-associated microbiomes (phytobiomes) is underappreciated, and plant niches are hotspots of bacterial S-metabolism with implications for S emissions. Building upon emerging findings, we posit that coordination of S-metabolism between plants and phytobiomes is a common mechanism for plant-microbe homeostasis and agriculturally beneficial microbial services.
View Article and Find Full Text PDFAnal Chim Acta
May 2025
College of Textile Science and Engineering, Jiangnan University, 1800Lihu Road, Wuxi, 214122, China. Electronic address:
Flexible sweat sensors possess the special potential for continuous non-invasive monitoring of human blood glucose. We put forward a flexible microcolumn array sensor, which is designed for health monitoring by means of detecting glucose levels in sweat and capturing physiological signals related to human movement. With the combination of silk fibroin (SF), waterborne polyurethane (PU), and multi-walled carbon nanotubes (MWCNT), this microcolumn film electrode is able to effectively function as a strain sensor benefiting from the superior mechanical performance of PU.
View Article and Find Full Text PDFJ Genet Eng Biotechnol
March 2025
Centre for Bioinformatics, M.D. University, Rohtak, Haryana, India. Electronic address:
The emergence of multidrug resistanceagainst several antifungal drugs and the absence of alternate therapy limits the treatment choices leading to the spread of Candida auris infections, especially inimmunocompromised patients. This work aims to construct the multi-epitope vaccine using an immuno-informatics approachdue to the lack of efficient treatments for C. auris.
View Article and Find Full Text PDFJ Genet Eng Biotechnol
March 2025
Department of Bioinformatics, University of North Bengal, District-Darjeeling, West Bengal 734013, India. Electronic address:
Background: Acquired Immunodeficiency Syndrome (AIDS) is a critical global health issue caused by the human immunodeficiency virus (HIV). It has different strains and subtypes; among these, Subtype C accounts for higher infection rates than others. Despite its high prevalence, the molecular interactions with host receptors, specifically CD4, have not yet been explored.
View Article and Find Full Text PDFSLAS Technol
March 2025
Sygnature Discovery Ltd., BioCity, Pennyfoot Street, Nottingham, United Kingdom.
Drug discovery is a collaborative endeavor that often involves scientists from various disciplines and global collaborators. Efficient real-time sharing and updating of design-make-test-analyze (DMTA) information remains a challenge in drug discovery, hindering timely decision-making and project advancement. We propose a novel approach utilizing existing electronic inventory systems as DMTA workflow tracking platforms.
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