The mysteries behind immune aging and its related inflammation are being unmasked. The research of Jin et al. reveals that the defective turnover of damaged mitochondria in CD4 T cells from aged individuals results in the exacerbated secretion of mitochondrial DNA, fuelling inflammaging and impairing immune responses.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615384 | PMC |
http://dx.doi.org/10.1038/s43587-023-00412-2 | DOI Listing |
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