Case Report: Double trouble: a rare case of successfully treated and co-infection.

Background: Extra-urogenital infections due to () are rare, particularly co-infection with (). Herein, we report on a patient who was co-infected and successfully treated despite delayed treatment.

Case Presentation: We reported the case of a 43-year-old man with and co-infection after a traffic accident. The patient developed a fever and severe infection despite postoperative antimicrobial therapies. The blood culture of wound tissues was positive for Meanwhile, culturing of blood and wound samples showed pinpoint-sized colonies on blood agar plates and fried-egg-type colonies on mycoplasma medium, which were identified as by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA sequencing. Based on antibiotic susceptibility and symptoms, ceftazidime-avibactam and moxifloxacin were administered for infection. Meanwhile, after the failure of a series of anti-infective agents, and co-infection was successfully treated with a minocycline-based regimen and polymyxin B.

Conclusion: The co-infection with and was successfully treated with anti-infective agents despite delayed treatment, providing information for the management of double infection.