Alveolar bone loss is widespread in all age groups and remains a severe hazard to periodontal health. Horizontal alveolar bone loss is the pattern of bone loss more commonly seen in periodontitis. Until now, limited regenerative procedures have been applied to treating horizontal alveolar bone loss in periodontal clinics, making it the least predictable periodontal defect type. This article reviews the literature on recent advances in horizontal alveolar bone regeneration. The biomaterials and clinical and preclinical approaches tested for the regeneration of the horizontal type of alveolar bone are first discussed. Furthermore, current obstacles for horizontal alveolar bone regeneration and future directions in regenerative therapy are presented to provide new ideas for developing an effective multidisciplinary strategy to address the challenge of horizontal alveolar bone loss.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1088/1748-605X/acd672 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Absence of c-Maf and IL-10 enables type I IFN enhancement of innate responses to LPS in alveolar macrophages.
J Immunol
March 2025
Department of Veterinary and Animal Sciences, University of Massachusetts Amherst, Amherst, MA, United States.
Alveolar macrophages (AMs) are lung-resident myeloid cells and airway sentinels for inhaled pathogens and environmental particles. While AMs can be highly inflammatory in response to respiratory viruses, they do not mount proinflammatory responses to all airborne pathogens. For example, we previously showed that AMs fail to mount a robust proinflammatory response to Mycobacterium tuberculosis.
View Article and Find Full Text PDFInfluence of buccal bone lamella defects on hard and soft tissues with submerged and non-submerged healing in immediate implants - an experimental study in minipigs.
Int J Implant Dent
March 2025
Department of Prosthodontics, Propaedeutics and Dental Materials, Christian-Albrechts University at Kiel, Arnold-Heller-Strasse 16, Kiel, Germany.
Purpose: This study assessed the impact of the buccal bone on hard and soft tissues in submerged and non-submerged immediate implants using a minipig model.
Methods: Sixty-five titanium implants (Camlog Progressive Line) were placed in four minipigs immediately after tooth extraction. All non-submerged (NSM) implants received a mechanically induced buccal bone defect (NSM-BD), whereas the submerged group (SM) was classified as defective (SM-BD) and intact (SM-BI).
Managing Donor Site Pain After Alveolar Bone Grafting: A Comparative Analysis of Liposomal Bupivacaine (Exparel), Bupivacaine-Soaked Gelfoam, and ON-Q Ropivacaine.
J Craniofac Surg
March 2025
Michael E. DeBakey Department of Surgery, Division of Plastic Surgery, Baylor College of Medicine.
Introduction: Traditionally, alveolar bone grafting (ABG) uses bone from the iliac crest for repair. Harvesting this graft has been associated with significant donor site pain. Local anesthetic is a useful adjunct to alleviate postoperative opioid requirements.
View Article and Find Full Text PDFAdvancing Peri-Implantitis Treatment: A Scoping Review of Breakthroughs in Implantoplasty and Er:YAG Laser Therapies.
Clin Exp Dent Res
February 2025
Department of Periodontics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Background: Peri-implantitis represents a significant challenge in dental implantology, characterized by inflammatory reactions around osseointegrated dental implants that lead to progressive alveolar bone loss.
Objectives: To generate a scoping review that evaluates the efficacy of implantoplasty and Er:YAG laser therapies in managing peri-implantitis by synthesizing recent evidence on their impact on key clinical parameters-including probing depth reduction, bleeding on probing improvement, and marginal bone level stabilization-and to explore the potential synergistic benefits of combining these modalities for enhanced treatment outcomes.
Material And Methods: A comprehensive search was conducted in PubMed, EMBASE, the Cochrane Library, and Web of Science for studies published from January 2018 to the present.
Nociceptor Neurons Facilitate Orthodontic Tooth Movement via Piezo2 in Mice.
J Dent Res
March 2025
Department of Neural and Pain Sciences, School of Dentistry, University of Maryland Baltimore. Center to Advance Chronic Pain Research, Baltimore, MD, USA.
Multiple sensory afferents, including mechanosensitive and nociceptive nerves, are projected to the periodontium. Peptidergic afferents expressing transient receptor potential vanilloid 1 (TRPV1), a receptor for capsaicin, mediate pain caused by orthodontic forces. However, their role in orthodontic force-induced alveolar bone remodeling is poorly understood as is the contribution of mechanosensitive ion channels such as Piezo2 in nociceptive nerves.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!