Pairing a cue (e.g., an image of a geometrical figure) with an outcome (e.g., an image with aversive content) can result in the cue eliciting thoughts of that outcome (i.e., thought conditioning). Previous research suggests an advantage of counterconditioning over extinction in reducing thoughts of (aversive) outcomes. However, it is unclear how robust this effect is. This study aimed to (1) replicate the previously observed advantage of counterconditioning over extinction and (2) test whether counterconditioning leads to less reinstatement of thoughts of an aversive outcome relative to extinction. Participants (N = 118) underwent a differential conditioning procedure and were then assigned to one of three conditions: extinction (i.e., the aversive outcome was no longer presented), no extinction (i.e., the aversive outcome continued to be presented) and counterconditioning (i.e., the aversive outcome was replaced with positive images). After three unsignaled outcome presentations, participants indicated in a return of fear test the extent to which they thought of the aversive outcome. As predicted, counterconditioning was more successful in reducing thinking of the aversive outcome than extinction. Yet, there were no differences in return of thoughts of the aversive outcome between the two conditions. Future research should consider other return of fear procedures.
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http://dx.doi.org/10.1016/j.brat.2023.104320 | DOI Listing |
Sci Rep
January 2025
Radiological Techniques Department, College of Health and Medical Techniques, AL-Mustaqbal University, Hillah, Babil, 51001, Iraq.
This paper proposes a hybrid stochastic-robust optimization framework for sizing a photovoltaic/tidal/fuel cell (PV/TDL/FC) system to meet an annual educational building demand based on hydrogen storage via unscented transformation (UT), and information gap decision theory-based risk-averse strategy (IGDT-RA). The hybrid framework integrates the strengths of UT for scenario generation and IGDT-RA (hybrid UT-IGDT-RA) for optimizing the system robustness and maximum uncertainty radius (MRU) of building energy demand and renewable resource generation. The deterministic model focuses on minimizing the cost of energy production over the project's lifespan (CEPLS) and considers a reliability constraint defined as the demand shortage probability (DSHP).
View Article and Find Full Text PDFThe medial prefrontal cortex (mPFC) is required for learning associations that determine whether animals approach or avoid potential threats in the environment. Dopaminergic (DA) projections from the ventral tegmental area (VTA) to the mPFC carry information, particularly about aversive outcomes, that may inform prefrontal computations. But the role of prefrontal DA in learning based on aversive outcomes remains poorly understood.
View Article and Find Full Text PDFHCA Healthc J Med
December 2024
Del Sol Medical Center, El Paso, Texas.
Background: Addiction affects millions of people, often resulting from a complex interplay between genetic and environmental factors, and is frequently linked to mental health disorders. Many experts agree there is no cure for addiction, but there are effective treatments available. Many patients continue to succumb to addiction despite treatment.
View Article and Find Full Text PDFNat Cancer
January 2025
Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR, USA.
Patients with metastatic pancreatic ductal adenocarcinoma survive longer if disease spreads to the lung but not the liver. Here we generated overlapping, multi-omic datasets to identify molecular and cellular features that distinguish patients whose disease develops liver metastasis (liver cohort) from those whose disease develops lung metastasis without liver metastases (lung cohort). Lung cohort patients survived longer than liver cohort patients, despite sharing the same tumor subtype.
View Article and Find Full Text PDFPsychoneuroendocrinology
December 2024
Department of Psychological Science, University of Arkansas, Fayetteville, USA.
How does stress influence our decision-making? Although numerous studies have attempted to answer this question, their results have been inconsistent-presumably due to methodological heterogeneity. Drawing on cumulative prospect theory, we examined how acute stress influenced risky decision-making. To this end, we randomly assigned 147 participants to an acute stress induction or control condition and subsequently assessed participants' risky decision-making.
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