AI Article Synopsis
- Osteoarthritis has been identified in dinosaur skeletons from 50-70 million years ago, Egyptian mummies, and ancient English skeletons, indicating its long history in various species.
- The condition affects joints like the hands, spine, hips, knees, and feet, and can be classified as primary osteoarthritis when no prior injury exists, or secondary if linked to prior trauma or other factors.
- Osteoarthritis prevalence increases with age, and while there's evidence of inflammation involved, the exact cause, especially for primary osteoarthritis, remains unclear.
Article Abstract
The clinical appearance and radiological pattern of osteoarthritis have been identified in the skeletons of dinosaurs some 50-70 million years old, and in Egyptian mummies, and in ancient skeletons in England. Osteoarthritis patterns of joint involvement, often referred to as primary osteoarthritis, can be seen in the hands, spinal facet joints, hips, knees and feet, but can also be termed secondary osteoarthritis when seen in any joint that has had trauma, sepsis, surgery or metabolic insult. The prevalence of osteoarthritis increases with age. The histology and pathophysiology both demonstrate an inflammatory process. While there have been studies of genetic predisposition, the basic cause of primary osteoarthritis has not been determined.
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| http://dx.doi.org/10.1007/s10787-023-01223-y | DOI Listing |
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