Long-term needs of a family whose child has cancer must be integrated into the family's responsibilities early in the disease treatment. The family's understanding, acceptance, and participation in the patient's care is a determining factor in the effectiveness of the treatment plan. Family responsibilities are twofold: obtain correct medical information about child's disease and its treatment, and adapt to necessary changes in lifestyle. Basic medical knowledge the family must possess includes information relating to the disease, its expected course, treatment, and side effects. Adaptation to changes requires that parents be informed to the anticipated alterations in family and community relationships. They need specific information about hospital policies and routines, financial resources, and expectations of the treatment plan in effort to adapt to the demands of long term care. The challenge in preparing a family is in acceptance of a philosophy that recognizes and values the family's contribution to care. Family members are a crucial part of the health care team. A positive and encouraging approach from professionals is essential to family acceptance of the disease and compliance with treatment.
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http://dx.doi.org/10.1002/1097-0142(19860715)58:2+<508::aid-cncr2820581315>3.0.co;2-e | DOI Listing |
Am Fam Physician
January 2025
Abrazo Family Medicine Residency, Phoenix, Arizona.
Common early childhood concerns and behaviors include sleep issues, thumb-sucking, pacifier use, picky eating, school readiness, and oral health. Family physicians must recognize when these indicate an underlying disorder and offer constructive and evidence-based strategies to support healthy child development and family well-being. Behavioral interventions and education to address sleep issues can alleviate stress and decrease fatigue for the whole family.
View Article and Find Full Text PDFFront Public Health
January 2025
School of Midwifery, College of Health Sciences, Woldia University, Woldia, Ethiopia.
Background: The term "danger signs" refers to any symptoms or indicators that suggest a pregnant woman may be at risk during pregnancy. Mothers are often burdened with responsibilities, and the majority of them do not even receive treatment for potential complications, which can ultimately lead to the loss of their lives. This situation highlights the barriers that prevent them from being properly prepared for potential risks.
View Article and Find Full Text PDFMol Biol Rep
January 2025
Department of Structural and Molecular Biology, University College London, London, WC1E 6BT, UK.
Background: Ribosomal protein S6 kinase 1 (p70S6K1) is a member of the AGC family of serine/threonine kinases which plays a role in various cellular processes, including protein synthesis, cell growth, and survival. Dysregulation of p70S6K1, characterized by its overexpression and/or hyperactivation, has been implicated in numerous human pathologies, particularly in several types of cancer. Therefore, generating active, recombinant p70S6K1 is critical for investigating its role in cancer biology and for developing novel diagnostic or therapeutic approaches.
View Article and Find Full Text PDFPediatrics
January 2025
Center for Translational Science/Children's Research Institute, Children's National Hospital, Washington, District of Columbia.
Background And Objective: To evaluate the efficacy of Family-Centered Advance Care Planning for Teens With Cancer (FACE-TC) on adolescents' quality of life.
Methods: A clinical trial randomized adolescent-family dyads at a 2:1 ratio to either FACE-TC or control. FACE-TC dyads received 3 weekly 60-minute sessions: Lyon Pediatric Advance Care Planning Survey; Next Steps: Respecting Choices; and Five Wishes.
Curr Pharm Biotechnol
January 2025
Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
The SARS-CoV-2 pandemic has highlighted the need for society, as a whole, to be prepared against potential pandemics caused by a variety of different viral families of concern. Here, we describe a roadmap towards the identification and validation of conserved T cell epitope regions from Viral Families of Pandemic Potential (VFPP). For each viral family, we select a prototype virus, the sequence of which could be utilized in epitope identification screens.
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