Background: The study aims to determine the survival and recurrence rates of pilonidal sinus disease (PSD) carcinoma.
Methods: The data were collected retrospectively by searching the worldwide literature for all reports of carcinoma developing on the background of PSD. The results were presented using Kaplan-Meier curves.
Results: Between 1900 and 2022, 140 cases of PSD carcinoma were published in 103 papers, with follow-up data available in 111 cases. Squamous cell carcinoma constituted 94.6% of the cases (n = 105). The disease-specific survival rate was 61.7% for 3 years, 59.8% for 5 years, and 53.2% for 10 years. There was a significant survival difference between stages: 80.0% in stages I and II, 70.8% in stage III, and 47.8% in stage IV (p = 0.01). The 5-year survival in G1-tumors was better than G2 and G3-tumors at 70.5% and 32.0%, respectively (p = 0.002). Recurrence occurred in 46.6% of the patients. The time-to-recurrence in patients treated with curative intention averaged 15.1 months (1-132 months). Local, regional, and distant recurrence was observed in 75.6%, 33.3%, and 28.9% of the recurrent tumors, respectively.
Conclusions: Pilonidal sinus carcinoma has a worse prognosis than primary cutaneous squamous cell carcinoma. Poor prognostic factors include advanced-stage disease and poor differentiation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jso.27319 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Trephination for primary pediatric pilonidal sinus disease: medium term functional and recurrence outcome of a large cohort.
Pediatr Surg Int
December 2024
Department of Pediatric Surgery, Shamir Medical Center, Be'er Ya'acov, Israel.
Purpose: Minimal incision procedures have been recommended for pediatric pilonidal sinus disease, based on small studies with short follow-up. We aimed to describe medium-term outcomes of trephination in a large cohort.
Methods: Retrospective chart review and additional concluding telephone interviews for all children who underwent primary trephination in our institution over 5.
Subarachnoid anesthesia for sacrococcygeal pilonidal disease treatment: A case report.
Medicine (Baltimore)
December 2024
Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China.
Rationale: Sacrococcygeal pilonidal disease (SPD) is a chronic inflammatory condition primarily affecting young males. This case report details the perioperative anesthetic management of a patient undergoing SPD surgery under subarachnoid anesthesia.
Patient Concerns: A 48-year-old obese male (body mass index 28 kg/m2) presented with recurrent sacrococcygeal swelling, pain, and purulent discharge for 2 months.
Sinus laser therapy versus Karydakis flap procedure in the management of pilonidal sinus disease: a comparative analysis of intraoperative parameters and postoperative outcome.
Tech Coloproctol
December 2024
Department of General Surgery, Altinbas University Faculty of Medicine Medical Park Bahcelievler Hospital, Istanbul, Turkey.
Background: This study aimed to investigate the utility of minimally invasive sinus laser therapy (SiLaT) versus flap surgery (Karydakis flap procedure) in terms of intraoperative parameters and postoperative outcome in patients with pilonidal sinus disease (PSD).
Methods: A total of 106 patients with PSD (mean ± SD age: 26.4 ± 7.
Pilonidal sinus laser therapy.
J Visc Surg
December 2024
Département de chirurgie digestive, hôpital Charles-Nicolle, CHU de Rouen, 1, rue de Germont, 76000 Rouen, France. Electronic address:
Utility of Keystone Flap in Armory of Dermatosurgeons.
Indian J Dermatol
October 2024
Department of Burns and Plastic Surgery and Hypospadias and VVFs Clinic, Postgraduate Institute of Medical Sciences (PGIMS), University of Health Sciences, Rohtak (UHSR), Haryana, India.
Purpose And Background: To create awareness among dermatosurgeons about the versatility of keystone flaps in re-surfacing post-excisional small, medium and large skin defects.
Aims And Objectives: Single-staged tension-free re-surfacing of various sized skin defects using keystone flap and to have least donor site morbidity, primary healing and maximum functional outcome.
Material And Methods: This retrospective study was conducted, between October 2021 - January 2023 in Department of Plastic Surgery, PGIMS Rohtak, on 15 males and 1 female aged between 18 - 65 years.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!